Concepedia

Cofactor-mediated Stabilization

Cofactor-Mediated Stabilization is a biocatalyst stabilization mechanism in which the structural and functional integrity of an enzyme is enhanced through specific interactions with its cofactor, thereby reducing conformational fluctuations and increasing resistance to denaturation.

31

Publications

992

Citations

147

Authors

63

Institutions

Publications per year

2017–2026

6

Parents

Publications

31

The Cofactor-mediated Regulation of Apoenzyme Levels in Animal Tissues

Olga Greengard, Maria Gordon · Journal of Biological Chemistry · 1963 · 116 citations · Full text

, , +16

Coenzyme Q supplementation or over-expression of the yeast Coq8 putative kinase stabilizes multi-subunit Coq polypeptide complexes in yeast coq null mutants

Cuiwen He, Letian Xie, Christopher M. Allan et al. · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · 2014 · 97 citations · Full text

, , +14

Synthesis of Vibegron Enabled by a Ketoreductase Rationally Designed for High pH Dynamic Kinetic Reduction

Feng Xu, Birgit Kosjek, Fabien L. Cabirol et al. · Angewandte Chemie International Edition · 2018 · 59 citations

, , +17

The Multidomain Thioredoxin-Monothiol Glutaredoxins Represent a Distinct Functional Group

Bastian Hoffmann, Marta A. Uzarska, Carsten Berndt et al. · Antioxidants and Redox Signaling · 2011 · 54 citations

, , +15

Role of the Coenzyme in the Stabilization of Glyceraldehyde-3-phosphate Dehydrogenase

P Elödi, G Szabolcsi · Nature · 1959 · 46 citations

, , +12

1–5 of 31

Authors

147

  1. WR
    Wolfram Ruf

    Scripps Research Institute, United States

    2 publications · 77 citations

    2

    h-index

  2. RJ
    Ramona J. Petrovan

    Scripps Research Institute, United States

    2 publications · 77 citations

    2

    h-index

  3. ZL
    Zhuqing Liu

    Shanghai Tenth People's Hospital, China

    1 publications · 59 citations

    1

    h-index

  4. VB
    Vinciane Blaise

    University of Liège, Belgium

    1 publications · 26 citations

    1

    h-index

  5. GF
    Georges Feller

    University of Liège, Belgium

    1 publications · 26 citations

    1

    h-index

1–5 of 147

Institutions

63

  1. Scripps Research Institute

    San Diego, United States

    3 h-index

    5 publications

    197 citations

  2. University of Pennsylvania

    Philadelphia, United States

    1 h-index

    3 publications

    102 citations

  3. Tsinghua University

    Beijing, China

    1 h-index

    2 publications

    42 citations

  4. Université de Lorraine

    Nancy, France

    1 h-index

    3 publications

    42 citations

  5. University of Wisconsin–Madison

    Madison, United States

    1 h-index

    4 publications

    164 citations

  6. Westchester Institute for Human Development

    Valhalla, United States

    1 h-index

    2 publications

    232 citations

  7. University of Liège

    Liège, Belgium

    1 h-index

    6 publications

    156 citations

  8. University of Southern California

    Los Angeles, United States

    1 h-index

    1 publications

    10 citations

1–8 of 63

Venues

  1. Journal of Biological Chemistry

    JBC · 5 publications · 217 citations

    5

    h-index

  2. Biochemistry

    4 publications · 113 citations

    4

    h-index

  3. Archives of Biochemistry and Biophysics

    ABB · 2 publications · 40 citations

    2

    h-index

  4. Angewandte Chemie International Edition

    2 publications · 93 citations

    2

    h-index

  5. Nature Chemical Biology

    1 publications · 38 citations

    1

    h-index

1–5