Concepedia

Cofactor-mediated Group Transfer

Cofactor-Mediated Group Transfer is a biochemical process in which a cofactor facilitates the transfer of a functional group between substrates by transiently binding and stabilizing the group during catalysis, thereby enabling specific and efficient transformation that distinguishes it from direct substrate-to-substrate transfer mechanisms.

8

Publications

603

Citations

27

Authors

17

Institutions

Publications per year

2017–2026

1

Parents

Publications

8

Direct transfer of extended groups from synthetic cofactors by DNA methyltransferases

Christian Dalhoff, Saulius Klimašauskas, Elmar G. Weinhold · Nature Chemical Biology · 2005 · 248 citations

, , +15

The Occurrence of a Group Transfer Involving Enzyme (phosphoglucomutase) and Substrate

Victor A. Najjar, Maynard E. Pullman · Science · 1954 · 135 citations

, , +7

Group-Translocation: A Consequence of Enzyme-Catalysed Group-Transfer

Peter Mitchell, Jennifer Moyle · Nature · 1958 · 86 citations

, , +11

Engineering the DNA cytosine-5 methyltransferase reaction for sequence-specific labeling of DNA

Audronė Lapinaitė, Giedrė Urbanavičiūtė, Rūta Gerasimaitė et al. · Nucleic Acids Research · 2012 · 51 citations · Full text

, , +14

Investigation of Metal Ion Binding in Phosphonoacetaldehyde Hydrolase Identifies Sequence Markers for Metal-Activated Enzymes of the HAD Enzyme Superfamily<sup>,</sup>

Guofeng Zhang, Marc C. Morais, Jianying Dai et al. · Biochemistry · 2004 · 38 citations

, , +17

1–5 of 8

Authors

27

  1. SK
    Saulius Klimašauskas

    Vilnius University, Lithuania

    2 publications · 299 citations

    2

    h-index

  2. JM
    Jennifer Moyle

    Bodmin Hospital, United Kingdom

    1 publications · 86 citations

    1

    h-index

  3. GZ
    Guofeng Zhang

    Shanxi University, China

    1 publications · 38 citations

    1

    h-index

  4. JD
    Jianying Dai

    Boston University, United States

    1 publications · 38 citations

    1

    h-index

  5. ME
    Maynard E. Pullman

    Johns Hopkins University, United States

    1 publications · 135 citations

    1

    h-index

1–5 of 27

Institutions

17

  1. Czech Academy of Sciences, Institute of Biotechnology

    Prague, Czechia

    1 h-index

    1 publications

    248 citations

  2. The University of Osaka

    Osaka, Japan

    1 h-index

    1 publications

    17 citations

  3. Johns Hopkins Hospital

    Baltimore, United States

    1 h-index

    2 publications

    270 citations

  4. Boston University

    Boston, United States

    1 h-index

    6 publications

    228 citations

  5. University of Konstanz

    Konstanz, Germany

    1 h-index

    2 publications

    26 citations

  6. University of New Mexico

    Albuquerque, United States

    1 h-index

    6 publications

    228 citations

  7. RWTH Aachen University

    Aachen, Germany

    1 h-index

    2 publications

    496 citations

  8. The Graduate University for Advanced Studies, SOKENDAI

    Hayama, Japan

    1 h-index

    4 publications

    68 citations

1–8 of 17

Venues

  1. Antonie van Leeuwenhoek

    1 publications · 15 citations

    1

    h-index

  2. Nucleic Acids Research

    1 publications · 51 citations

    1

    h-index

  3. Nature

    1 publications · 86 citations

    1

    h-index

  4. Biochemistry

    1 publications · 38 citations

    1

    h-index

  5. FEBS Letters

    1 publications · 13 citations

    1

    h-index

1–5