Concepedia

Cofactor-dependent Transamination

Cofactor-Dependent Transamination is a biochemical reaction mechanism, belonging to the class of transamination processes, that specifically requires the participation of a cofactor—most commonly pyridoxal phosphate (PLP)—to facilitate the transfer of an amino group between amino acids and keto acids, thereby distinguishing it from cofactor-independent aminotransferase mechanisms.

61

Publications

2.3K

Citations

172

Authors

74

Institutions

Publications per year

2017–2026

4

Parents

Publications

61

Ornithine-δ-transaminase in the rat I. Assay and some general properties

Carl Peraino, Henry C. Pitot · Biochimica et Biophysica Acta (BBA) - Specialized Section on Enzymological Subjects · 1963 · 164 citations

, , +6

A purified cysteine conjugate beta-lyase from rat kidney cytosol. Requirement for an alpha-keto acid or an amino acid oxidase for activity and identity with soluble glutamine transaminase K.

James Stevens, Joe D. Robbins, R. Andrew Byrd · Journal of Biological Chemistry · 1986 · 156 citations · Full text

, , +11

FUNCTION OF THE VITAMIN B6 GROUP: PYRIDOXAL PHOSPHATE (CODECARBOXYLASE) IN TRANSAMINATION

Herman C. Lichstein, I. C. Gunsalus, W. W. Umbreit · Journal of Biological Chemistry · 1945 · 117 citations · Full text

, , +15

The effect of substituents on the feasibility of azomethine-azomethine isomerization: New synthetic opportunities for biomimetic transamination

Vadim A. Soloshonok, Taizo Ono · Tetrahedron · 1996 · 90 citations

, , +7

Studies on the Specificity of Tyrosine-α-ketoglutarate Transaminase

George A. Jacoby, Bert N. La Du · Journal of Biological Chemistry · 1964 · 89 citations · Full text

, , +8

1–5 of 61

Authors

172

  1. FW
    Frederick W. Barnes

    Johns Hopkins Medicine, United States

    5 publications · 166 citations

    5

    h-index

  2. AN
    Alfred Nisonoff

    University of Illinois Urbana-Champaign, United States

    3 publications · 122 citations

    3

    h-index

  3. TE
    Theodore Enns

    Johns Hopkins University, United States

    3 publications · 75 citations

    3

    h-index

  4. SS
    Sarah S. Henry

    Johns Hopkins Medicine, United States

    2 publications · 80 citations

    2

    h-index

  5. MK
    M.Ya. Karpeisky

    Engelhardt Institute of Molecular Biology, Russia

    2 publications · 66 citations

    2

    h-index

1–5 of 172

Institutions

74

  1. Johns Hopkins Medicine

    Baltimore, United States

    5 h-index

    15 publications

    487 citations

  2. Johns Hopkins University

    Baltimore, United States

    5 h-index

    15 publications

    487 citations

  3. National Institutes of Health

    Bethesda, United States

    2 h-index

    4 publications

    234 citations

  4. The University of Texas at Austin

    Austin, United States

    2 h-index

    5 publications

    152 citations

  5. Max Planck Institute of Biochemistry

    Martinsried, Germany

    2 h-index

    7 publications

    163 citations

  6. Karolinska Institutet

    Stockholm, Sweden

    2 h-index

    3 publications

    52 citations

  7. Columbia University

    New York, United States

    2 h-index

    6 publications

    346 citations

  8. Technical University of Denmark

    Kongens Lyngby, Denmark

    2 h-index

    3 publications

    82 citations

1–8 of 74

Venues

  1. Journal of Biological Chemistry

    JBC · 20 publications · 938 citations

    17

    h-index

  2. Nature

    3 publications · 108 citations

    3

    h-index

  3. Biochemistry

    3 publications · 135 citations

    3

    h-index

  4. Archives of Biochemistry and Biophysics

    ABB · 3 publications · 51 citations

    3

    h-index

  5. Journal of the American Chemical Society

    JACS · 2 publications · 121 citations

    2

    h-index

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