Concepedia

Cofactor-dependent Reductive Reactions

Cofactor-Dependent Reductive Reactions is a biochemical process in which the reduction of a substrate is catalyzed through the transfer of electrons from a specific cofactor, thereby distinguishing it from cofactor-independent reductions by its obligatory reliance on a non-protein organic or inorganic cofactor to facilitate redox transformations within metabolic pathways.

11

Publications

513

Citations

41

Authors

15

Institutions

Publications per year

2017–2026

2

Parents

Publications

11

The corrinoid cofactor of reductive dehalogenases affects dechlorination rates and extents in organohalide-respiring <i>Dehalococcoides mccartyi</i>

Jun Yan, Burcu Şimşir, Abigail T. Farmer et al. · The ISME Journal · 2015 · 79 citations · Full text

, , +14

Importance of Substrate and Cofactor Polarization in the Active Site of Dihydrofolate Reductase

Mireia Garcia‐Viloca, Donald G. Truhlar, Jiali Gao · Journal of Molecular Biology · 2003 · 77 citations

, , +14

α-Secondary Isotope Effects as Probes of “Tunneling-Ready” Configurations in Enzymatic H-Tunneling:  Insight from Environmentally Coupled Tunneling Models

Christopher R. Pudney, Sam Hay, Michael J. Sutcliffe et al. · Journal of the American Chemical Society · 2006 · 73 citations

, , +17

Role of Active Site Tyrosine Residues in Catalysis by Human Glutathione Reductase

R. Luise Krauth‐Siegel, L. David Arscott, Annette Schönleben‐Janas et al. · Biochemistry · 1998 · 73 citations

, , +16

Crystal structure of human mARC1 reveals its exceptional position among eukaryotic molybdenum enzymes

Christian Kubitza, Florian Bittner, Carsten Ginsel et al. · Proceedings of the National Academy of Sciences · 2018 · 59 citations · Full text

, , +17

1–5 of 11

Authors

41

  1. AT
    Abigail T. Farmer

    University of Tennessee at Knoxville, United States

    1 publications · 79 citations

    1

    h-index

  2. DC
    David Chuang

    The University of Texas Southwestern Medical Center, United States

    1 publications · 17 citations

    1

    h-index

  3. CC
    Cooper Citek

    Stanford University, United States

    1 publications · 42 citations

    1

    h-index

  4. RH
    R. Heiner Schirmer

    Max Planck Institute for Medical Research, Germany

    1 publications · 73 citations

    1

    h-index

  5. DR
    Diana R. Tomchick

    The University of Texas Southwestern Medical Center, United States

    1 publications · 17 citations

    1

    h-index

1–5 of 41

Institutions

15

  1. Max Planck Institute for Terrestrial Microbiology

    Marburg, Germany

    1 h-index

    1 publications

    24 citations

  2. University of Michigan

    Ann Arbor, United States

    1 h-index

    5 publications

    365 citations

  3. Indian Institute of Chemical Biology

    Kolkata, India

    1 h-index

    2 publications

    36 citations

  4. Heidelberg University

    Tiffin, United States

    1 h-index

    5 publications

    365 citations

  5. University of Manchester

    Manchester, United Kingdom

    1 h-index

    4 publications

    292 citations

  6. University of Tennessee at Knoxville

    Knoxville, United States

    1 h-index

    7 publications

    553 citations

  7. Heidelberg University

    Heidelberg, Germany

    1 h-index

    5 publications

    365 citations

  8. Christian-Albrechts-Universität zu Kiel

    Kiel, Germany

    1 h-index

    5 publications

    295 citations

1–8 of 15

Venues

  1. Journal of the American Chemical Society

    JACS · 2 publications · 115 citations

    2

    h-index

  2. Journal of Biological Chemistry

    JBC · 2 publications · 32 citations

    2

    h-index

  3. FEMS Microbiology Letters

    1 publications · 24 citations

    1

    h-index

  4. The ISME Journal

    1 publications · 79 citations

    1

    h-index

  5. Journal of Molecular Biology

    JMB · 1 publications · 77 citations

    1

    h-index

1–5