Concepedia

Cofactor Affinity Optimization

Cofactor Affinity Optimization is a biochemical engineering strategy that systematically modifies enzyme-cofactor binding interactions to enhance catalytic efficiency and specificity through targeted alterations in cofactor binding site architecture.

8

Publications

360

Citations

47

Authors

20

Institutions

Publications per year

2017–2026

2

Parents

Publications

8

A General Tool for Engineering the NAD/NADP Cofactor Preference of Oxidoreductases

Jackson K. B. Cahn, Caroline A. Werlang, Armin Baumschlager et al. · ACS Synthetic Biology · 2016 · 155 citations · Full text

, , +17

Mining the cellular inventory of pyridoxal phosphate-dependent enzymes with functionalized cofactor mimics

Annabelle Hoegl, Matthew B. Nodwell, Volker C. Kirsch et al. · Nature Chemistry · 2018 · 61 citations

, , +16

Optimization of conditions for the catalytic effect of the factor IXa - Factor VIII complex

Susan Elödi, Katalin Váradi · Thrombosis Research · 1979 · 54 citations

, , +15

Mutations Increasing Cofactor Affinity, Improve Stability and Activity of a Baeyer–Villiger Monooxygenase

Hamid R. Mansouri, Oriol Gracia Carmona, Julia Jodlbauer et al. · ACS Catalysis · 2022 · 29 citations · Full text

, , +17

The production of ω-hydroxy palmitic acid using fatty acid metabolism and cofactor optimization in Escherichia coli

Changmin Sung, Eunok Jung, Kwon‐Young Choi et al. · Applied Microbiology and Biotechnology · 2015 · 25 citations

, , +17

1–5 of 8

Authors

47

  1. VC
    Volker C. Kirsch

    Technical University of Munich, Germany

    1 publications · 61 citations

    1

    h-index

  2. JH
    Jin H. Bae

    Harvard University, United States

    1 publications · 25 citations

    1

    h-index

  3. KV
    Katalin Váradi

    Baxter (Austria), Austria

    1 publications · 54 citations

    1

    h-index

  4. LC
    Letícia Christina Pires Gonçalves

    Universidade de São Paulo, Brazil

    1 publications · 29 citations

    1

    h-index

  5. MF
    M. Fink

    Max Planck Institute for Astrophysics, Germany

    1 publications · 29 citations

    1

    h-index

1–5 of 47

Institutions

20

  1. Institut de Chimie de Nice

    Nice, France

    1 h-index

    1 publications

    29 citations

  2. Georgia Institute of Technology

    Atlanta, United States

    1 h-index

    1 publications

    29 citations

  3. Center for Integrated Protein Science Munich

    Munich, Germany

    1 h-index

    8 publications

    488 citations

  4. Jeonnam Bioindustry Foundation

    Naju, South Korea

    1 h-index

    1 publications

    25 citations

  5. TU Wien

    Vienna, Austria

    1 h-index

    6 publications

    174 citations

  6. Division of Chemistry

    Arlington, United States

    1 h-index

    6 publications

    930 citations

  7. Consejo Nacional de Investigaciones Científicas y Técnicas

    Buenos Aires, Argentina

    1 h-index

    1 publications

    29 citations

  8. Université Côte d'Azur

    Nice, France

    1 h-index

    1 publications

    29 citations

1–8 of 20

Venues

  1. ACS Synthetic Biology

    1 publications · 155 citations

    1

    h-index

  2. Journal of Pharmaceutical Sciences

    1 publications · 11 citations

    1

    h-index

  3. Thrombosis Research

    1 publications · 54 citations

    1

    h-index

  4. Biochemical and Biophysical Research Communications

    BBRC · 1 publications · 15 citations

    1

    h-index

  5. ACS Catalysis

    1 publications · 29 citations

    1

    h-index

1–5