Concepedia

Codeine Pharmacogenetics

Codeine Pharmacogenetics is a pharmacogenetic framework that elucidates the influence of genetic variation in the CYP2D6 enzyme on the metabolic activation of codeine to morphine, thereby determining interindividual differences in analgesic response and adverse drug reactions.

56

Publications

6K

Citations

246

Authors

128

Institutions

Publications per year

2017–2026

7

Parents

Publications

56

Codeine Intoxication Associated with Ultrarapid CYP2D6 Metabolism

Yvan Gasche, Youssef Daali, Marc Fathi et al. · New England Journal of Medicine · 2004 · 700 citations · Full text

, , +17

Pharmacogenetics of morphine poisoning in a breastfed neonate of a codeine-prescribed mother

Gideon Koren, James Cairns, David Chitayat et al. · The Lancet · 2006 · 678 citations

, , +16

Clinical Pharmacogenetics Implementation Consortium Guidelines for Cytochrome P450 2D6 Genotype and Codeine Therapy: 2014 Update

Kristine R. Crews, Andrea Gaedigk, Henry M. Dunnenberger et al. · Clinical Pharmacology & Therapeutics · 2014 · 678 citations · Full text

, , +17

Clinical Pharmacogenetics Implementation Consortium Guideline for <i>CYP2D6</i>, <i>OPRM1</i>, and <i>COMT</i> Genotypes and Select Opioid Therapy

Kristine R. Crews, Andrew A. Monte, Rachel Huddart et al. · Clinical Pharmacology & Therapeutics · 2021 · 399 citations · Full text

, , +17

Clinical Pharmacogenetics Implementation Consortium (CPIC) Guidelines for Codeine Therapy in the Context of Cytochrome P450 2D6 (CYP2D6) Genotype

Kristine R. Crews, Andrea Gaedigk, Henry M. Dunnenberger et al. · Clinical Pharmacology & Therapeutics · 2011 · 368 citations · Full text

, , +17

1–5 of 56

Authors

246

  1. GK
    Gideon Koren

    Hospital for Sick Children, Canada

    11 publications · 1.4K citations

    11

    h-index

  2. BC
    Bruce Carleton

    University of British Columbia, Canada

    8 publications · 343 citations

    9

    h-index

  3. CJ
    Colin J.D. Ross

    University of British Columbia, Canada

    7 publications · 288 citations

    8

    h-index

  4. MR
    Michael R. Hayden

    University of British Columbia, Canada

    6 publications · 258 citations

    7

    h-index

  5. AG
    Andrea Gaedigk

    Children's Mercy Hospital, United States

    7 publications · 2.5K citations

    7

    h-index

1–5 of 246

Institutions

128

  1. Hospital for Sick Children

    Toronto, Canada

    11 h-index

    31 publications

    2.3K citations

  2. University of British Columbia

    Vancouver, Canada

    8 h-index

    25 publications

    1.2K citations

  3. Child and Family Research Institute

    Vancouver, Canada

    6 h-index

    19 publications

    842 citations

  4. Children's Mercy Hospital

    Kansas City, United States

    6 h-index

    10 publications

    4.5K citations

  5. University of Toronto

    Toronto, Canada

    6 h-index

    13 publications

    880 citations

  6. The University of Adelaide

    Adelaide, Australia

    5 h-index

    12 publications

    910 citations

  7. Western University

    London, Canada

    4 h-index

    12 publications

    1.1K citations

  8. Stanford University

    Stanford, United States

    4 h-index

    8 publications

    2.6K citations

1–8 of 128

Venues

  1. Clinical Pharmacology & Therapeutics

    CPT · 8 publications · 2K citations

    8

    h-index

  2. PubMed

    Repository · 4 publications · 129 citations

    5

    h-index

  3. Therapeutic Drug Monitoring

    3 publications · 197 citations

    3

    h-index

  4. 3

    h-index

  5. British Journal of Clinical Pharmacology

    BJCP · 3 publications · 239 citations

    3

    h-index

1–5