Concepedia

Coagulation Amplification

Coagulation Amplification is a biochemical mechanism within the extrinsic pathway of hemostasis that intensifies thrombin generation through the positive feedback activation of coagulation factors, particularly by activated factor VIIa-mediated enhancement of factor IX and factor X activation.

62

Publications

6.1K

Citations

239

Authors

95

Institutions

Publications per year

2017–2026

13

Parents

Publications

62

A Cell-based Model of Hemostasis

Dougald M. Monroe, Maureane Hoffman · Thrombosis and Haemostasis · 2001 · 1.5K citations

, , +17

An Enzyme Cascade in the Blood Clotting Mechanism, and its Function as a Biochemical Amplifier

Robert Macfarlane · Nature · 1964 · 1.1K citations

, , +16

The Roles of Protein C and Thrombomodulin in the Regulation of Blood Coagulation

CT Esmon · Journal of Biological Chemistry · 1989 · 1.1K citations · Full text

, , +17

Evolution of blood coagulation activators and inhibitors in the healthy human fetus

Pascale Reverdiau, B. Delahousse, G. Body et al. · Blood · 1996 · 242 citations · Full text

, , +14

Different strategies to develop an electrochemical thrombin aptasensor

Mònica Mir, Mark Vreeke, Ioanis Katakis · Electrochemistry Communications · 2006 · 161 citations

, , +14

1–5 of 62

Authors

239

  1. DM
    Dougald M. Monroe

    University of North Carolina at Chapel Hill, United States

    3 publications · 1.7K citations

    3

    h-index

  2. OD
    Oscar D. Ratnoff

    Case Western Reserve University, United States

    3 publications · 154 citations

    3

    h-index

  3. FA
    Frederick A. Ofosu

    McMaster University, Canada

    3 publications · 142 citations

    3

    h-index

  4. LS
    Lindsay Smith

    McMaster University, Canada

    2 publications · 109 citations

    2

    h-index

  5. CO
    Cristina Ocaña

    Universitat Autònoma de Barcelona, Spain

    2 publications · 48 citations

    2

    h-index

1–5 of 239

Institutions

95

  1. McMaster University

    Hamilton, Canada

    3 h-index

    14 publications

    715 citations

  2. University of North Carolina at Chapel Hill

    Chapel Hill, United States

    3 h-index

    9 publications

    503 citations

  3. Case Western Reserve University

    Cleveland, United States

    3 h-index

    5 publications

    206 citations

  4. Canadian Red Cross Society

    Ottawa, Canada

    3 h-index

    10 publications

    521 citations

  5. University Hospitals of Cleveland

    Cleveland, United States

    3 h-index

    5 publications

    206 citations

  6. University School

    Cleveland, United States

    2 h-index

    2 publications

    128 citations

  7. Oklahoma Medical Research Foundation

    Oklahoma City, United States

    2 h-index

    2 publications

    1.1K citations

  8. Howard Hughes Medical Institute

    Chevy Chase, United States

    2 h-index

    2 publications

    1.1K citations

1–8 of 95

Venues

  1. Biosensors and Bioelectronics

    7 publications · 350 citations

    7

    h-index

  2. Biochemical Journal

    BJ · 5 publications · 187 citations

    5

    h-index

  3. Thrombosis and Haemostasis

    5 publications · 1.7K citations

    5

    h-index

  4. Blood

    4 publications · 346 citations

    4

    h-index

  5. Journal of Biological Chemistry

    JBC · 4 publications · 1.1K citations

    4

    h-index

1–5