Closed-loop Therapeutic Systems

Closed-Loop Therapeutic Systems is a biomedical intervention framework that continuously monitors physiological signals and autonomously adjusts therapeutic stimulation in real time based on feedback, distinguishing it from open-loop systems through its dynamic, adaptive regulation of treatment.

Publications

1.6K

Citations

230

Authors

107

Institutions

Publications per year

2017–2026

Parents

Implantable Microsystems

Publications

Multinational Study of Subcutaneous Model-Predictive Closed-Loop Control in Type 1 Diabetes Mellitus: Summary of the Results

Boris Kovatchev, Claudio Cobelli, Éric Renard et al. · Journal of Diabetes Science and Technology · 2010 · 199 citations · Full text

Medicine, Endocrinology, Internal Medicine +17

Staying in the Loop: Relational Agency and Identity in Next-Generation DBS for Psychiatry

Sara Goering, Eran Klein, Darin D. Dougherty et al. · AJOB Neuroscience · 2017 · 119 citations

Life Sciences, Neuroscience, Psychiatry +17

Feasibility of a Portable Bihormonal Closed-Loop System to Control Glucose Excursions at Home Under Free-Living Conditions for 48 Hours

Arianne C. van Bon, Yoeri M. Luijf, Rob Koebrugge et al. · Diabetes Technology & Therapeutics · 2013 · 74 citations

Medicine, Endocrinology, Internal Medicine +15

Clinical Opportunities for Continuous Biosensing and Closed-Loop Therapies

Jason Li, Jia Liang, Steven J. Laken et al. · Trends in Chemistry · 2020 · 66 citations

Engineering, Bioengineering, Biomedical Engineering +16

WINCS Harmoni: Closed-loop dynamic neurochemical control of therapeutic interventions

Kendall H. Lee, J. Luis Luján, James K. Trevathan et al. · Scientific Reports · 2017 · 62 citations · Full text

Life Sciences, Neurology, Neuroscience +17

1–5 of 42

Authors

230

RH
Roman Hovorka
University of Cambridge, United Kingdom
4 publications · 108 citations
4
h-index
CK
Charlotte K. Boughton
Wellcome/MRC Institute of Metabolic Science, United Kingdom
3 publications · 79 citations
3
h-index
SH
Sara Hartnell
Cambridge University Hospitals NHS Foundation Trust, United Kingdom
3 publications · 79 citations
3
h-index
AL
Andrew L. Ko
University of Washington, United States
3 publications · 149 citations
3
h-index
HC
H.J. Chizeck
University of Washington, United States
3 publications · 127 citations
3
h-index

1–5 of 230

Institutions

107

1–8 of 107

Venues

Journal of Diabetes Science and Technology
DST · 4 publications · 277 citations
4
h-index
Journal of Neural Engineering
3 publications · 156 citations
3
h-index
Diabetes Technology & Therapeutics
3 publications · 131 citations
3
h-index
Frontiers in Neuroscience
3 publications · 73 citations
3
h-index
PubMed
Repository · 2 publications · 38 citations
2
h-index

1–5