Concepedia

Clonal Selection Modeling

Clonal Selection Modeling is a computational framework within immune system modeling that formalizes the clonal selection theory by simulating the activation, proliferation, and differentiation of lymphocytes in response to antigenic stimuli, distinguishing itself through its focus on affinity-based selection and mutation mechanisms in adaptive immune responses.

61

Publications

4.2K

Citations

153

Authors

77

Institutions

Publications per year

2017–2026

10

Parents

Publications

61

Theoretical studies of clonal selection: Minimal antibody repertoire size and reliability of self-non-self discrimination

Alan S. Perelson, George Oster · Journal of Theoretical Biology · 1979 · 652 citations

, , +15

A Modification of Jerne's Theory of Antibody Production using the Concept of Clonal Selection

F. M. Bürnet · CA A Cancer Journal for Clinicians · 1976 · 507 citations · Full text

, , +3

A Modification of Jerne's Theory of Antibody Production using the Concept of Clonal Selection.

F. M. Bürnet · Australian journal of science · 1957 · 494 citations

, , +3

The clonal selection theory of acquired immunity

Michael Heidelberger · Archives of Biochemistry and Biophysics · 1960 · 383 citations

, , +9

A general framework for modeling tumor-immune system competition and immunotherapy: Mathematical analysis and biomedical inferences

Alberto d’Onofrio · Physica D Nonlinear Phenomena · 2005 · 287 citations · Full text

, , +17

1–5 of 61

Authors

153

  1. GI
    George I. Bell

    Los Alamos National Laboratory, United States

    4 publications · 355 citations

    4

    h-index

  2. JD
    Jonathan Desponds

    Centre National de la Recherche Scientifique, France

    2 publications · 65 citations

    2

    h-index

  3. SG
    Shangce Gao

    University of Toyama, Japan

    2 publications · 33 citations

    2

    h-index

  4. MP
    Mario Pavone

    University of Catania, Italy

    2 publications · 74 citations

    2

    h-index

  5. FM
    F. M. Bürnet

    Walter and Eliza Hall Institute of Medical Research, Australia

    2 publications · 1K citations

    2

    h-index

1–5 of 153

Institutions

77

  1. Los Alamos National Laboratory

    Los Alamos, United States

    5 h-index

    5 publications

    1K citations

  2. Xidian University

    Xi'an, China

    2 h-index

    8 publications

    227 citations

  3. Donghua University

    Shanghai, China

    2 h-index

    7 publications

    110 citations

  4. University of Toyama

    Toyama, Japan

    2 h-index

    5 publications

    82 citations

  5. Institute of Mathematics

    Warsaw, Poland

    2 h-index

    4 publications

    100 citations

  6. Heidelberg University

    Heidelberg, Germany

    2 h-index

    6 publications

    390 citations

  7. Shanghai Jiao Tong University

    Shanghai, China

    2 h-index

    5 publications

    224 citations

  8. University of Colorado Anschutz Medical Campus

    Aurora, United States

    2 h-index

    2 publications

    188 citations

1–8 of 77

Venues

  1. Journal of Theoretical Biology

    4 publications · 959 citations

    4

    h-index

  2. Canadian Journal of Forest Research

    2 publications · 51 citations

    2

    h-index

  3. bioRxiv (Cold Spring Harbor Laboratory)

    Repository · 2 publications · 58 citations

    2

    h-index

  4. Applied Soft Computing

    2 publications · 48 citations

    2

    h-index

  5. Nature

    2 publications · 79 citations

    2

    h-index

1–5