Concepedia

Clock Protein Dimerization

Clock Protein Dimerization is a molecular mechanism in circadian biology whereby two clock proteins associate to form a functional heterodimer or homodimer, thereby enabling transcriptional regulation of circadian rhythm genes through DNA binding and cooperative protein interactions.

48

Publications

8.2K

Citations

224

Authors

82

Institutions

Publications per year

2017–2026

4

Parents

Publications

48

Role of the CLOCK Protein in the Mammalian Circadian Mechanism

Nicholas Gekakis, David Staknis, Hubert B. Nguyen et al. · Science · 1998 · 2K citations

, , +16

The basic-helix–loop–helix-PAS orphan MOP3 forms transcriptionally active complexes with circadian and hypoxia factors

John B. Hogenesch, Yi-Zhong Gu, Sanjay Jain et al. · Proceedings of the National Academy of Sciences · 1998 · 789 citations

, , +17

A bioluminescence resonance energy transfer (BRET) system: Application to interacting circadian clock proteins

Yao Xu, David W. Piston, Carl Hirschie Johnson · Proceedings of the National Academy of Sciences · 1999 · 607 citations · Full text

, , +17

Isolation of <i>timeless</i> by PER Protein Interaction: Defective Interaction Between <i>timeless</i> Protein and Long-Period Mutant PER <sup>L</sup>

Nicholas Gekakis, Lino Sáez, Anne-Marie Delahaye-Brown et al. · Science · 1995 · 369 citations

, , +16

Crystal Structure of the Heterodimeric CLOCK:BMAL1 Transcriptional Activator Complex

Nian Huang, Yogarany Chelliah, Yongli Shan et al. · Science · 2012 · 358 citations · Full text

, , +17

1–5 of 48

Authors

224

  1. MI
    Masahiro Ishiura

    Nagoya University, Japan

    6 publications · 261 citations

    6

    h-index

  2. RI
    Ryo Iwase

    Nagoya University, Japan

    5 publications · 243 citations

    5

    h-index

  3. TU
    Tatsuya Uzumaki

    Nagoya University, Japan

    5 publications · 243 citations

    5

    h-index

  4. EW
    Eva Wolf

    Max Planck Institute of Molecular Physiology, Germany

    4 publications · 302 citations

    4

    h-index

  5. MM
    Megumi Morishita

    Nagoya University, Japan

    4 publications · 148 citations

    4

    h-index

1–5 of 224

Institutions

82

  1. Nagoya University

    Nagoya, Japan

    9 h-index

    50 publications

    2.8K citations

  2. Howard Hughes Medical Institute

    Chevy Chase, United States

    6 h-index

    23 publications

    19.8K citations

  3. Vanderbilt University

    Nashville, United States

    4 h-index

    16 publications

    2.9K citations

  4. Max Planck Institute of Molecular Physiology

    Dortmund, Germany

    4 h-index

    12 publications

    1K citations

  5. The University of Osaka

    Osaka, Japan

    4 h-index

    12 publications

    390 citations

  6. Japan Science and Technology Agency

    Tokyo, Japan

    4 h-index

    7 publications

    685 citations

  7. Tohoku University

    Sendai, Japan

    3 h-index

    20 publications

    3.2K citations

  8. Texas A&M University

    College Station, United States

    3 h-index

    12 publications

    1.1K citations

1–8 of 82

Venues

  1. Journal of Biological Chemistry

    JBC · 7 publications · 645 citations

    7

    h-index

  2. Science

    5 publications · 3.1K citations

    5

    h-index

  3. Proceedings of the National Academy of Sciences

    PNAS · 5 publications · 1.7K citations

    5

    h-index

  4. Genes to Cells

    4 publications · 207 citations

    4

    h-index

  5. Biochemical and Biophysical Research Communications

    BBRC · 3 publications · 274 citations

    3

    h-index

1–5