Concepedia

Clamp Loader-polymerase Coordination

Clamp Loader-Polymerase Coordination is a molecular mechanism that governs the spatiotemporal coupling of the clamp loader's ATP-dependent loading of the sliding clamp onto DNA with the polymerase's recruitment and processive DNA synthesis activity during replication.

12

Publications

1.1K

Citations

48

Authors

27

Institutions

Publications per year

2017–2026

1

Parents

Publications

12

The internal workings of a DNA polymerase clamp‐loading machine

Jennifer Turner, Manju Hingorani, Zvi Kelman et al. · The EMBO Journal · 1999 · 222 citations · Full text

, , +11

A Molecular Switch in a Replication Machine Defined by an Internal Competition for Protein Rings

Vytautas Naktinis, Jennifer Turner, Mike O’Donnell · Cell · 1996 · 154 citations · Full text

, , +16

Competitive processivity‐clamp usage by DNA polymerases during DNA replication and repair

Francisco J. López de Saro · The EMBO Journal · 2003 · 135 citations · Full text

, , +16

A direct proofreader–clamp interaction stabilizes the Pol III replicase in the polymerization mode

Slobodan Jergic, Nicholas P Horan, Mohamed M. Elshenawy et al. · The EMBO Journal · 2013 · 105 citations · Full text

, , +11

Creating a dynamic picture of the sliding clamp during T4 DNA polymerase holoenzyme assembly by using fluorescence resonance energy transfer

Michael A. Trakselis, Stephen C. Alley, Ernesto Abel‐Santos et al. · Proceedings of the National Academy of Sciences · 2001 · 103 citations · Full text

, , +17

1–5 of 12

Authors

48

  1. MO
    Mike O’Donnell

    Howard Hughes Medical Institute, United States

    4 publications · 489 citations

    4

    h-index

  2. SJ
    Stephen J. Benkovic

    Pennsylvania State University, United States

    3 publications · 213 citations

    3

    h-index

  3. MA
    Michael A. Trakselis

    University of Pittsburgh, United States

    2 publications · 152 citations

    2

    h-index

  4. JT
    Jennifer Turner

    Howard Hughes Medical Institute, United States

    2 publications · 376 citations

    2

    h-index

  5. YC
    Yuanyuan Chen

    Zhejiang Cancer Hospital, China

    1 publications · 26 citations

    1

    h-index

1–5 of 48

Institutions

27

  1. Howard Hughes Medical Institute

    Chevy Chase, United States

    5 h-index

    8 publications

    891 citations

  2. Rockefeller University

    New York, United States

    4 h-index

    8 publications

    737 citations

  3. Pennsylvania State University

    State College, United States

    3 h-index

    8 publications

    632 citations

  4. Cornell University

    Ithaca, United States

    2 h-index

    5 publications

    906 citations

  5. University of Wollongong

    Wollongong, Australia

    2 h-index

    11 publications

    1.1K citations

  6. Illawarra Health and Medical Research Institute

    Keiraville, Australia

    1 h-index

    1 publications

    69 citations

  7. Harvard University

    Cambridge, United States

    1 h-index

    2 publications

    210 citations

  8. Academy of Scientific and Innovative Research

    Ghaziabad, India

    1 h-index

    2 publications

    138 citations

1–8 of 27

Venues

  1. The EMBO Journal

    3 publications · 462 citations

    3

    h-index

  2. Proceedings of the National Academy of Sciences

    PNAS · 2 publications · 164 citations

    2

    h-index

  3. 1

    h-index

  4. 1

    h-index

  5. Molecular and Cellular Biology

    MCB · 1 publications · 68 citations

    1

    h-index

1–5