Concepedia

Clamp Loader Conformational Dynamics

Clamp Loader Conformational Dynamics is a biophysical mechanism that characterizes the ATP-driven structural rearrangements in the clamp loader complex essential for the recognition, opening, and placement of the sliding clamp onto DNA during replication initiation.

16

Publications

996

Citations

65

Authors

28

Institutions

Publications per year

2017–2026

2

Parents

Publications

16

Mechanism of Processivity Clamp Opening by the Delta Subunit Wrench of the Clamp Loader Complex of E. coli DNA Polymerase III

David Jeruzalmi, Olga Yurieva, Yanxiang Zhao et al. · Cell · 2001 · 264 citations · Full text

, , +17

ATP Binding to the Escherichia coli Clamp Loader Powers Opening of the Ring-shaped Clamp of DNA Polymerase III Holoenzyme

Manju Hingorani, Mike O’Donnell · Journal of Biological Chemistry · 1998 · 141 citations · Full text

, , +15

Clamp loader ATPases and the evolution of DNA replication machinery

Brian A. Kelch, Débora L. Makino, Mike O’Donnell et al. · BMC Biology · 2012 · 109 citations · Full text

, , +17

Ordered ATP Hydrolysis in the γ Complex Clamp Loader AAA+ Machine

Aaron M. Johnson, Mike O’Donnell · Journal of Biological Chemistry · 2003 · 76 citations · Full text

, , +8

Biochemical characterization of a clamp-loader complex homologous to eukaryotic replication factor C from the hyperthermophilic archaeon Sulfolobus solfataricus 1 1Edited by M. Gottesman

Francesca M. Pisani, Mariarita De Felice, Floriana Carpentieri et al. · Journal of Molecular Biology · 2000 · 59 citations

, , +15

1–5 of 16

Authors

65

  1. MO
    Mike O’Donnell

    Howard Hughes Medical Institute, United States

    8 publications · 736 citations

    8

    h-index

  2. JK
    John Kuriyan

    Howard Hughes Medical Institute, United States

    4 publications · 442 citations

    4

    h-index

  3. LB
    Linda B. Bloom

    University of Florida, United States

    3 publications · 103 citations

    3

    h-index

  4. CO
    Christopher O. Paschall

    Howard Hughes Medical Institute, United States

    2 publications · 77 citations

    2

    h-index

  5. MH
    Manju Hingorani

    Wesleyan University, United States

    2 publications · 405 citations

    2

    h-index

1–5 of 65

Institutions

28

  1. Howard Hughes Medical Institute

    Chevy Chase, United States

    8 h-index

    25 publications

    3K citations

  2. Rockefeller University

    New York, United States

    8 h-index

    18 publications

    2.8K citations

  3. University of Florida

    Gainesville, United States

    3 h-index

    14 publications

    559 citations

  4. Lawrence Berkeley National Laboratory

    Berkeley, United States

    3 h-index

    4 publications

    214 citations

  5. University of California, Berkeley

    Berkeley, United States

    3 h-index

    10 publications

    570 citations

  6. Pohang University of Science and Technology

    Pohang, South Korea

    1 h-index

    3 publications

    42 citations

  7. Federal Scientific Research Centre Crystallography and Photonics

    Moscow, Russia

    1 h-index

    1 publications

    39 citations

  8. University of Illinois Urbana-Champaign

    Urbana, United States

    1 h-index

    2 publications

    50 citations

1–8 of 28

Venues

  1. Journal of Biological Chemistry

    JBC · 6 publications · 357 citations

    6

    h-index

  2. Journal of Molecular Biology

    JMB · 3 publications · 122 citations

    3

    h-index

  3. Structure

    2 publications · 72 citations

    2

    h-index

  4. Cell

    1 publications · 264 citations

    1

    h-index

  5. BMC Biology

    1 publications · 109 citations

    1

    h-index

1–5