Concepedia

Circular Permutation Engineering

Circular Permutation Engineering is a protein engineering methodology that involves the rearrangement of a protein’s sequence topology by connecting its original termini and introducing new termini elsewhere to create structurally and functionally altered variants while preserving the overall native fold.

32

Publications

2.3K

Citations

132

Authors

50

Institutions

Publications per year

2017–2026

5

Parents

Publications

32

A transposase strategy for creating libraries of circularly permuted proteins

Manan Mehta, Shirley Liu, Jonathan J. Silberg · Nucleic Acids Research · 2012 · 1.1K citations · Full text

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Cyclic Green Fluorescent Protein Produced in Vivo Using an Artificially Split PI-PfuI Intein from Pyrococcus furiosus

Hideo Iwaï, Andreas Lingel, Andreas Plückthun · Journal of Biological Chemistry · 2001 · 151 citations · Full text

, , +8

Improving the Catalytic Activity of <i>Candida</i> <i>antarctica</i> Lipase B by Circular Permutation

Zhen Qian, Stefan Lutz · Journal of the American Chemical Society · 2005 · 146 citations

, , +17

Random circular permutation of genes and expressed polypeptide chains: application of the method to the catalytic chains of aspartate transcarbamoylase.

Roney Graf, H. K. Schachman · Proceedings of the National Academy of Sciences · 1996 · 95 citations

, , +14

Circular Permutations in the Molecular Evolution of DNA Methyltransferases

Albert Jeltsch · Journal of Molecular Evolution · 1999 · 84 citations

, , +7

1–5 of 32

Authors

132

  1. SL
    Stefan Lutz

    Emory University, United States

    5 publications · 294 citations

    5

    h-index

  2. JJ
    Jonathan J. Silberg

    Rice University, United States

    3 publications · 1.1K citations

    3

    h-index

  3. SL
    Shirley Liu

    Yale University, United States

    2 publications · 1.1K citations

    2

    h-index

  4. JT
    Joshua T. Atkinson

    Rice University, United States

    2 publications · 36 citations

    2

    h-index

  5. AM
    Alicia M. Jones

    Rice University, United States

    2 publications · 36 citations

    2

    h-index

1–5 of 132

Institutions

50

  1. Emory University

    Atlanta, United States

    6 h-index

    10 publications

    638 citations

  2. Rice University

    Houston, United States

    3 h-index

    12 publications

    3.3K citations

  3. National Tsing Hua University

    Hsinchu, Taiwan

    2 h-index

    6 publications

    216 citations

  4. Massachusetts Institute of Technology

    Cambridge, United States

    2 h-index

    2 publications

    44 citations

  5. University of California, Berkeley

    Berkeley, United States

    2 h-index

    5 publications

    295 citations

  6. National Yang Ming Chiao Tung University

    Hsinchu, Taiwan

    2 h-index

    6 publications

    202 citations

  7. The Seoul Institute

    Seoul, South Korea

    1 h-index

    1 publications

    20 citations

  8. Johns Hopkins Medicine

    Baltimore, United States

    1 h-index

    6 publications

    120 citations

1–8 of 50

Venues

  1. Journal of the American Chemical Society

    JACS · 4 publications · 278 citations

    4

    h-index

  2. Nucleic Acids Research

    3 publications · 1.1K citations

    3

    h-index

  3. Proceedings of the National Academy of Sciences

    PNAS · 3 publications · 191 citations

    3

    h-index

  4. Biochemistry

    3 publications · 67 citations

    3

    h-index

  5. ChemBioChem

    2 publications · 74 citations

    2

    h-index

1–5