Concepedia

Chromatography Scale-up

Chromatography Scale-Up is a methodological framework within chemical engineering that enables the systematic translation of laboratory-scale chromatographic separation processes to industrial-scale production while maintaining performance, resolution, and efficiency through predictive modeling and geometric and operational parameter optimization.

66

Publications

2.4K

Citations

250

Authors

91

Institutions

Publications per year

2017–2026

11

Parents

Publications

66

Continuous beds: high-resolving, cost-effective chromatographic matrices

Stellan Hjertén, Yifan Li, Jiali Liao et al. · Nature · 1992 · 164 citations

, , +12

Rapid purification and scale-up of honokiol and magnolol using high-capacity high-speed counter-current chromatography

Lijuan Chen, Qiang Zhang, Guangli Yang et al. · Journal of Chromatography A · 2007 · 124 citations

, , +13

Large-scale chromatography of recombinant proteins

Erich Hochuli · Journal of Chromatography A · 1988 · 102 citations

, , +12

Physical and mathematical modelling to aid scale-up of liquid chromatography

Graham H. Cowan, I.S. Gosling, J. F. Laws et al. · Journal of Chromatography A · 1986 · 102 citations

, , +13

Rapid linear scale-up of a protein separation by centrifugal partition chromatography

I. Sutherland, Grégoire Audo, Emma C. Bourton et al. · Journal of Chromatography A · 2008 · 78 citations

, , +15

1–5 of 66

Authors

250

  1. IS
    I. Sutherland

    Brunel University of London, United Kingdom

    11 publications · 575 citations

    11

    h-index

  2. PW
    Philip Wood

    Brunel University of London, United Kingdom

    6 publications · 254 citations

    6

    h-index

  3. SI
    Svetlana Ignatova

    Brunel University of London, United Kingdom

    6 publications · 350 citations

    6

    h-index

  4. IG
    Ian Garrard

    Brunel University of London, United Kingdom

    5 publications · 326 citations

    5

    h-index

  5. DJ
    David J. Hawes

    The University of Sydney, Australia

    5 publications · 212 citations

    5

    h-index

1–5 of 250

Institutions

91

  1. Brunel University of London

    London, United Kingdom

    13 h-index

    46 publications

    2.4K citations

  2. University College London

    London, United Kingdom

    4 h-index

    13 publications

    256 citations

  3. Centre National de la Recherche Scientifique

    Paris, France

    4 h-index

    10 publications

    186 citations

  4. Swansea University

    Swansea, United Kingdom

    3 h-index

    5 publications

    170 citations

  5. Technische Universität Braunschweig

    Braunschweig, Germany

    3 h-index

    7 publications

    193 citations

  6. Biochemical Society

    London, United Kingdom

    3 h-index

    7 publications

    114 citations

  7. Universidade Federal do Rio de Janeiro

    Rio de Janeiro, Brazil

    3 h-index

    6 publications

    158 citations

  8. Université de Pau et des Pays de l'Adour

    Pau, France

    2 h-index

    2 publications

    50 citations

1–8 of 91

Venues

  1. Journal of Chromatography A

    30 publications · 1.2K citations

    19

    h-index

  2. 6

    h-index

  3. Biotechnology Progress

    5 publications · 150 citations

    5

    h-index

  4. Biotechnology and Bioengineering

    4 publications · 102 citations

    4

    h-index

  5. Organic Process Research & Development

    3 publications · 66 citations

    3

    h-index

1–5