Concepedia

Chromatin Phase Separation

Chromatin Phase Separation is a biophysical mechanism in which chromatin regions undergo liquid-liquid phase separation to dynamically compartmentalize the genome into functionally distinct domains within the nuclear space.

188

Publications

24.2K

Citations

1.1K

Authors

373

Institutions

Publications per year

2017–2026

149

Variants

Chromatin Liquid-liquid Phase Separation

Parents

Publications

188

Coactivator condensation at super-enhancers links phase separation and gene control

Benjamin R. Sabari, Alessandra Dall’Agnese, Ann Boija et al. · Science · 2018 · 2.7K citations

, , +17

Phase separation drives heterochromatin domain formation

Amy R. Strom, Alexander Emelyanov, Mustafa Mir et al. · Nature · 2017 · 2K citations · Full text

, , +10

Transcription Factors Activate Genes through the Phase-Separation Capacity of Their Activation Domains

Ann Boija, Isaac A. Klein, Benjamin R. Sabari et al. · Cell · 2018 · 1.9K citations · Full text

, , +16

Liquid droplet formation by HP1α suggests a role for phase separation in heterochromatin

Adam G. Larson, Daniel Elnatan, Madeline M Keenen et al. · Nature · 2017 · 1.8K citations

, , +14

Organization of Chromatin by Intrinsic and Regulated Phase Separation

Bryan A. Gibson, Lynda K. Doolittle, Liv Jensen et al. · Cell · 2019 · 1.1K citations · Full text

, , +12

1–5 of 188

Authors

1.1K

  1. CP
    Clifford P. Brangwynne

    Princeton University, United States

    9 publications · 1.2K citations

    9

    h-index

  2. GJ
    Geeta J. Narlikar

    University of California, San Francisco, United States

    9 publications · 3K citations

    9

    h-index

  3. AR
    Amy R. Strom

    Princeton University, United States

    6 publications · 2.5K citations

    6

    h-index

  4. SR
    Sy Redding

    Howard Hughes Medical Institute, United States

    5 publications · 3.2K citations

    5

    h-index

  5. XD
    Xavier Darzacq

    University of California, Berkeley, United States

    5 publications · 2.4K citations

    5

    h-index

1–5 of 1.1K

Institutions

373

  1. Howard Hughes Medical Institute

    Chevy Chase, United States

    16 h-index

    38 publications

    10.4K citations

  2. University of California, San Francisco

    San Francisco, United States

    13 h-index

    60 publications

    26.5K citations

  3. Princeton University

    Princeton, United States

    10 h-index

    56 publications

    6.7K citations

  4. Centre National de la Recherche Scientifique

    Paris, France

    9 h-index

    32 publications

    3.8K citations

  5. Peking University

    Beijing, China

    9 h-index

    42 publications

    3.2K citations

  6. University of California, Berkeley

    Berkeley, United States

    8 h-index

    37 publications

    11.8K citations

  7. University of Edinburgh

    Edinburgh, United Kingdom

    7 h-index

    34 publications

    1.3K citations

  8. Center for Life Sciences

    Beijing, China

    7 h-index

    34 publications

    6K citations

1–8 of 373

Venues

  1. Nature Communications

    16 publications · 1.2K citations

    16

    h-index

  2. bioRxiv (Cold Spring Harbor Laboratory)

    Repository · 18 publications · 350 citations

    14

    h-index

  3. Nature

    11 publications · 5.6K citations

    11

    h-index

  4. Molecular Cell

    9 publications · 1.6K citations

    9

    h-index

  5. eLife

    8 publications · 858 citations

    8

    h-index

1–5