Concepedia

Chromatin Compartmentalization

Chromatin Compartmentalization is a structural principle of genome organization that partitions the chromatin landscape into spatially and functionally distinct domains, primarily classified as active (A) and inactive (B) compartments, based on epigenetic states and gene expression potential.

100

Publications

11.2K

Citations

634

Authors

271

Institutions

Publications per year

2017–2026

54

Parents

Publications

100

Targeted Degradation of CTCF Decouples Local Insulation of Chromosome Domains from Genomic Compartmentalization

Elphège P. Nora, Anton Goloborodko, Anne-Laure Valton et al. · Cell · 2017 · 1.9K citations · Full text

, , +15

Heterochromatin drives compartmentalization of inverted and conventional nuclei

Martin Falk, Yana Feodorova, N. M. Naumova et al. · Nature · 2019 · 730 citations

, , +12

Chromatin organization by an interplay of loop extrusion and compartmental segregation

Johannes Nuebler, Geoffrey Fudenberg, Maxim Imakaev et al. · Proceedings of the National Academy of Sciences · 2018 · 724 citations · Full text

, , +17

DNA Sequence-Dependent Compartmentalization and Silencing of Chromatin at the Nuclear Lamina

Joseph Zullo, Ignacio A. Demarco, Roger Piqué-Regi et al. · Cell · 2012 · 457 citations · Full text

, , +14

Histone Modifications Regulate Chromatin Compartmentalization by Contributing to a Phase Separation Mechanism

Liang Wang, Yifei Gao, Xiangdong Zheng et al. · Molecular Cell · 2019 · 393 citations · Full text

, , +14

1–5 of 100

Authors

634

  1. JD
    Job Dekker

    University of Massachusetts Chan Medical School, United States

    8 publications · 3.5K citations

    8

    h-index

  2. LA
    Leonid A. Mirny

    Massachusetts Institute of Technology, United States

    6 publications · 3.4K citations

    6

    h-index

  3. MI
    Maxim Imakaev

    Massachusetts Institute of Technology, United States

    6 publications · 1.6K citations

    6

    h-index

  4. NA
    Nezar Abdennur

    Massachusetts Institute of Technology, United States

    6 publications · 2.7K citations

    6

    h-index

  5. SV
    Sergey V. Razin

    Institute of Gene Biology, Russia

    5 publications · 166 citations

    5

    h-index

1–5 of 634

Institutions

271

  1. Centre National de la Recherche Scientifique

    Paris, France

    11 h-index

    65 publications

    5.6K citations

  2. Howard Hughes Medical Institute

    Chevy Chase, United States

    9 h-index

    17 publications

    10.2K citations

  3. Massachusetts Institute of Technology

    Cambridge, United States

    9 h-index

    28 publications

    12.8K citations

  4. University of Massachusetts Chan Medical School

    Worcester, United States

    8 h-index

    29 publications

    11.4K citations

  5. Peking University

    Beijing, China

    6 h-index

    31 publications

    2.8K citations

  6. Inserm

    Paris, France

    5 h-index

    20 publications

    621 citations

  7. Institute of Gene Biology

    Moscow, Russia

    5 h-index

    20 publications

    655 citations

  8. Gladstone Institutes

    San Francisco, United States

    5 h-index

    7 publications

    7.2K citations

1–8 of 271

Venues

  1. bioRxiv (Cold Spring Harbor Laboratory)

    Repository · 9 publications · 187 citations

    9

    h-index

  2. The Journal of Cell Biology

    JCB · 7 publications · 1.3K citations

    7

    h-index

  3. Nature Communications

    5 publications · 420 citations

    5

    h-index

  4. Nucleic Acids Research

    4 publications · 180 citations

    4

    h-index

  5. Nature

    4 publications · 997 citations

    4

    h-index

1–5