Concepedia

Cholinergic Synaptic Toxicity

Cholinergic Synaptic Toxicity is a pathological process characterized by the selective impairment or degeneration of cholinergic synapses due to toxic insult, distinguishing it from other forms of synaptic toxicity by its specific targeting of neurons utilizing acetylcholine as a neurotransmitter.

150

Publications

7.7K

Citations

536

Authors

185

Institutions

Publications per year

2017–2026

9

Parents

Publications

150

Behavioral and neurochemical effects following neurotoxic lesions of a major cholinergic input to the cerebral cortex in the rat1

Charles Flicker, Richard Dean, Dorothy L. Watkins et al. · Pharmacology Biochemistry and Behavior · 1983 · 373 citations

, , +17

Neonatal exposure to polybrominated diphenyl ether (PBDE 153) disrupts spontaneous behaviour, impairs learning and memory, and decreases hippocampal cholinergic receptors in adult mice

Henrik Viberg · Toxicology and Applied Pharmacology · 2003 · 340 citations

, , +17

Long-term central cholinergic hypofunction induced in mice by ethylcholine aziridinium ion (AF64A) in vivo.

Alexander Fisher, C.R. Mantione, Donald J. Abraham et al. · Journal of Pharmacology and Experimental Therapeutics · 1982 · 220 citations

, , +17

AF64A, a cholinergic neurotoxin, selectively depletes acetylcholine in hippocampus and cortex, and produces long-term passive avoidance and radial-arm maze deficits in the rat

Thomas J. Walsh, Hugh A. Tilson, Diane L. DeHaven et al. · Brain Research · 1984 · 213 citations

, , +16

Dissociable effects on spatial maze and passive avoidance acquisition and retention following AMPA- and ibotenic acid-induced excitotoxic lesions of the basal forebrain in rats: Differential dependence on cholinergic neuronal loss

Keith J. Page, Barry J. Everitt, Trevor W. Robbins et al. · Neuroscience · 1991 · 207 citations

, , +17

1–5 of 150

Authors

536

  1. HV
    Henrik Viberg

    Uppsala University, Sweden

    6 publications · 842 citations

    6

    h-index

  2. AF
    Anders Fredriksson

    Uppsala University, Sweden

    6 publications · 389 citations

    6

    h-index

  3. IH
    Israel Hanin

    Loyola University Chicago, United States

    6 publications · 579 citations

    6

    h-index

  4. MJ
    María José Anadón

    Universidad Complutense de Madrid, Spain

    4 publications · 106 citations

    4

    h-index

  5. CP
    Carey Pope

    Oklahoma State University, United States

    4 publications · 99 citations

    4

    h-index

1–5 of 536

Institutions

185

  1. Uppsala University

    Uppsala, Sweden

    8 h-index

    21 publications

    2.1K citations

  2. University of Arizona

    Tucson, United States

    5 h-index

    15 publications

    1.1K citations

  3. Duke Medical Center

    Durham, United States

    5 h-index

    18 publications

    840 citations

  4. Oklahoma State University

    Stillwater, United States

    4 h-index

    12 publications

    292 citations

  5. University of Pittsburgh

    Pittsburgh, United States

    4 h-index

    6 publications

    196 citations

  6. Leipzig University

    Leipzig, Germany

    4 h-index

    13 publications

    473 citations

  7. Norwegian Defence Research Establishment

    Oslo, Norway

    4 h-index

    7 publications

    182 citations

  8. Universidad Complutense de Madrid

    Madrid, Spain

    4 h-index

    27 publications

    691 citations

1–8 of 185

Venues

  1. Brain Research

    17 publications · 931 citations

    17

    h-index

  2. Toxicology and Applied Pharmacology

    TAAP · 11 publications · 727 citations

    11

    h-index

  3. Neuroscience

    7 publications · 606 citations

    7

    h-index

  4. Toxicology

    7 publications · 155 citations

    7

    h-index

  5. Neurotoxicology and Teratology

    5 publications · 189 citations

    5

    h-index

1–5