Concepedia

Checkpoints Failure

Checkpoints Failure is a mechanistic defect in cell cycle regulatory systems wherein surveillance mechanisms fail to halt progression in response to DNA damage or replication stress, thereby permitting the propagation of genomic alterations.

5

Publications

393

Citations

25

Authors

17

Institutions

Publications per year

2017–2026

0

Parents

Publications

5

Checkpoint Failure and Chromosomal Instability without Lymphomagenesis in Mre11ATLD1/ATLD1 Mice

Jan-Willem F Theunissen, Mark I. Kaplan, Patricia A. Hunt et al. · Molecular Cell · 2003 · 172 citations · Full text

, , +16

Loss of Neuronal Cell Cycle Control in Ataxia-Telangiectasia: A Unified Disease Mechanism

Yan Yang, Karl Herrup · Journal of Neuroscience · 2005 · 131 citations · Full text

, , +17

Adenosine kinase inhibition promotes survival of fetal adenosine deaminase–deficient thymocytes by blocking dATP accumulation

C. Justin Van De Wiele, James G. Vaughn, Michael R. Blackburn et al. · Journal of Clinical Investigation · 2002 · 39 citations · Full text

, , +17

Adenosine kinase inhibition promotes survival of fetal adenosine deaminase–deficient thymocytes by blocking dATP accumulation

C. Justin Van De Wiele, James G. Vaughn, Michael R. Blackburn et al. · Journal of Clinical Investigation · 2002 · 35 citations · Full text

, , +17

SUMOylation of HP1α supports association with ncRNA to define responsiveness of breast cancer cells to chemotherapy

Feng-Ming Lin, Santosh Kumar, Jing Ren et al. · Oncotarget · 2016 · 16 citations · Full text

, , +14

1–5 of 5

Authors

25

  1. JG
    James G. Vaughn

    University of Oklahoma, United States

    2 publications · 74 citations

    2

    h-index

  2. CL
    Catherine Ledent

    Université Libre de Bruxelles, Belgium

    2 publications · 74 citations

    2

    h-index

  3. MA
    Marlene A. Jacobson

    United States Military Academy, United States

    2 publications · 74 citations

    2

    h-index

  4. HJ
    Hong Jiang

    Peking University, China

    2 publications · 74 citations

    2

    h-index

  5. CJ
    C. Justin Van De Wiele

    University of Oklahoma, United States

    2 publications · 74 citations

    2

    h-index

1–5 of 25

Institutions

17

  1. Université Libre de Bruxelles

    Brussels, Belgium

    2 h-index

    2 publications

    74 citations

  2. University of Oklahoma

    Norman, United States

    2 h-index

    3 publications

    109 citations

  3. Oklahoma Medical Research Foundation

    Oklahoma City, United States

    2 h-index

    8 publications

    296 citations

  4. United States Military Academy

    West Point, United States

    1 h-index

    1 publications

    35 citations

  5. University Hospitals Cleveland Medical Center

    Cleveland, United States

    1 h-index

    1 publications

    131 citations

  6. Merck Biopharma Co., Ltd. (Japan)

    Tokyo, Japan

    1 h-index

    1 publications

    39 citations

  7. Harvard University

    Cambridge, United States

    1 h-index

    2 publications

    344 citations

  8. The University of Texas MD Anderson Cancer Center

    Houston, United States

    1 h-index

    3 publications

    48 citations

1–8 of 17

Venues

  1. Journal of Clinical Investigation

    JCI · 2 publications · 74 citations

    2

    h-index

  2. Molecular Cell

    1 publications · 172 citations

    1

    h-index

  3. Journal of Neuroscience

    1 publications · 131 citations

    1

    h-index

  4. Oncotarget

    1 publications · 16 citations

    1

    h-index

1–4