Concepedia

Checkpoint Blockade Autoimmunity

Checkpoint Blockade Autoimmunity is a therapeutic-induced autoimmune phenomenon arising from the inhibition of immune checkpoint pathways, characterized by the loss of self-tolerance due to enhanced T-cell activation against autoantigens.

48

Publications

4.5K

Citations

411

Authors

123

Institutions

Publications per year

2017–2026

41

Variants

Ici-induced AutoimmunityImmune Checkpoint Inhibitor-induced Autoimmunity

Parents

Publications

48

Cancer regression and autoimmunity induced by cytotoxic T lymphocyte-associated antigen 4 blockade in patients with metastatic melanoma

Giao Q. Phan, James Chih‐Hsin Yang, Richard M. Sherry et al. · Proceedings of the National Academy of Sciences · 2003 · 1.6K citations · Full text

, , +17

Association of Autoimmune Encephalitis With Combined Immune Checkpoint Inhibitor Treatment for Metastatic Cancer

T.J. Williams, David Benavides, Kelly-Ann Patrice et al. · JAMA Neurology · 2016 · 277 citations

, , +17

<i>Bifidobacterium</i> can mitigate intestinal immunopathology in the context of CTLA-4 blockade

Feng Wang, Qian Yin, Liang Chen et al. · Proceedings of the National Academy of Sciences · 2017 · 228 citations · Full text

, , +17

Rheumatic immune-related adverse events of checkpoint therapy for cancer: case series of a new nosological entity

Cassandra Calabrese, E. Kirchner, Apostolos Kontzias et al. · RMD Open · 2017 · 197 citations · Full text

, , +16

Autoantibody Development under Treatment with Immune-Checkpoint Inhibitors

Emma C. de Moel, Elisa A. Rozeman, Ellen Kapiteijn et al. · Cancer Immunology Research · 2018 · 195 citations · Full text

, , +17

1–5 of 48

Authors

411

  1. LM
    Le Min

    Brigham and Women's Hospital, United States

    3 publications · 106 citations

    3

    h-index

  2. TE
    Trevor E. Angell

    Brigham and Women's Hospital, United States

    3 publications · 155 citations

    3

    h-index

  3. VT
    Venessa Tsang

    The University of Sydney, Australia

    2 publications · 212 citations

    2

    h-index

  4. FS
    F. Stephen Hodi

    Dana-Farber Cancer Institute, United States

    2 publications · 83 citations

    2

    h-index

  5. WB
    Wolfgang Boehmerle

    Charité - Universitätsmedizin Berlin, Germany

    2 publications · 67 citations

    2

    h-index

1–5 of 411

Institutions

123

  1. Harvard University

    Cambridge, United States

    6 h-index

    22 publications

    723 citations

  2. Brigham and Women's Hospital

    Boston, United States

    6 h-index

    34 publications

    1.4K citations

  3. Dana-Farber Cancer Institute

    Boston, United States

    4 h-index

    16 publications

    580 citations

  4. The University of Sydney

    Sydney, Australia

    3 h-index

    17 publications

    2K citations

  5. Melanoma Institute Australia

    Sydney, Australia

    3 h-index

    9 publications

    1.1K citations

  6. Diabetes Australia

    Canberra, Australia

    2 h-index

    5 publications

    414 citations

  7. Universitat de Barcelona

    Barcelona, Spain

    2 h-index

    5 publications

    345 citations

  8. Humboldt-Universität zu Berlin

    Berlin, Germany

    2 h-index

    19 publications

    679 citations

1–8 of 123

Venues

  1. Proceedings of the National Academy of Sciences

    PNAS · 4 publications · 1.9K citations

    4

    h-index

  2. The Journal of Clinical Endocrinology & Metabolism

    JCEM · 3 publications · 263 citations

    3

    h-index

  3. Frontiers in Immunology

    3 publications · 119 citations

    3

    h-index

  4. Journal for ImmunoTherapy of Cancer

    JITC · 2 publications · 167 citations

    2

    h-index

  5. The Journal of Immunology

    JI · 2 publications · 70 citations

    2

    h-index

1–5