Concepedia

Chassis Genome Engineering

Chassis Genome Engineering is a genome-scale synthetic biology methodology that involves the systematic design and construction of a minimal, optimized host organism genome intended to support specific biological functions or pathways by precisely removing non-essential elements while retaining core cellular viability and desired phenotypic capabilities.

13

Publications

534

Citations

104

Authors

47

Institutions

Publications per year

2017–2026

12

Parents

Publications

13

Rapid pathway prototyping and engineering using in vitro and in vivo synthetic genome SCRaMbLE-in methods

Wei Liu, Zhouqing Luo, Yun Wang et al. · Nature Communications · 2018 · 155 citations · Full text

, , +16

Rational construction of genome-reduced Burkholderiales chassis facilitates efficient heterologous production of natural products from proteobacteria

Jiaqi Liu, Haibo Zhou, Zhiyu Yang et al. · Nature Communications · 2021 · 60 citations · Full text

, , +14

Directed evolution of Escherichia coli with lower-than-natural plasmid mutation rates

Daniel E. Deatherage, Dacia Leon, Álvaro E. Rodriguez et al. · Nucleic Acids Research · 2018 · 45 citations · Full text

, , +17

High-Efficiency Multi-site Genomic Editing of Pseudomonas putida through Thermoinducible ssDNA Recombineering

Tomás Aparicio, Ákos Nyerges, Esteban Martínez‐García et al. · iScience · 2020 · 44 citations · Full text

, , +17

Engineering of a robust Escherichia coli chassis and exploitation for large-scale production processes

Martin Ziegler, Julia Zieringer, Clarissa-Laura Döring et al. · Metabolic Engineering · 2021 · 39 citations

, , +14

1–5 of 13

Authors

104

  1. WZ
    Wentao Zheng

    Shandong University, China

    1 publications · 60 citations

    1

    h-index

  2. YY
    Yasuo Yoshikuni

    Joint Genome Institute, United States

    1 publications · 20 citations

    1

    h-index

  3. CL
    Carole Lartigue

    Biologie du Fruit et Pathologie, France

    1 publications · 24 citations

    1

    h-index

  4. SC
    Stéphane Claverol

    Université de Bordeaux, France

    1 publications · 24 citations

    1

    h-index

  5. KO
    Koyo Ono

    Joint Genome Institute, United States

    1 publications · 20 citations

    1

    h-index

1–5 of 104

Institutions

47

  1. University of Chinese Academy of Sciences

    Beijing, China

    1 h-index

    2 publications

    30 citations

  2. Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement

    Paris, France

    1 h-index

    8 publications

    192 citations

  3. Joint Genome Institute

    Berkeley, United States

    1 h-index

    9 publications

    180 citations

  4. Université de Bordeaux

    Bordeaux, France

    1 h-index

    9 publications

    216 citations

  5. University of Helsinki

    Helsinki, Finland

    1 h-index

    3 publications

    78 citations

  6. Jiangnan University

    Wuxi, China

    1 h-index

    8 publications

    264 citations

  7. Hokkaido University

    Sapporo, Japan

    1 h-index

    1 publications

    20 citations

  8. Beijing Union University

    Beijing, China

    1 h-index

    1 publications

    15 citations

1–8 of 47

Venues

  1. Nature Communications

    2 publications · 215 citations

    2

    h-index

  2. ACS Synthetic Biology

    2 publications · 44 citations

    2

    h-index

  3. Metabolic Engineering

    2 publications · 56 citations

    2

    h-index

  4. Current Opinion in Systems Biology

    1 publications · 37 citations

    1

    h-index

  5. iScience

    1 publications · 44 citations

    1

    h-index

1–5