Concepedia

Chaperone-bound Intermediates

Chaperone-Bound Intermediates is a folding intermediate that is transiently associated with molecular chaperones during protein folding, distinguishing it from other folding intermediates by its specific stabilization and regulation through chaperone binding to prevent misfolding or aggregation.

37

Publications

4K

Citations

156

Authors

58

Institutions

Publications per year

2017–2026

3

Parents

Publications

37

Proteome-wide Analysis of Chaperonin-Dependent Protein Folding in Escherichia coli

Michael J. Kerner, Dean J. Naylor, Yasushi Ishihama et al. · Cell · 2005 · 666 citations · Full text

, , +17

Residues in chaperonin GroEL required for polypeptide binding and release

Wayne A. Fenton, Yechezkel Kashi, Krystyna Furtak et al. · Nature · 1994 · 642 citations

, , +14

Chaperonin‐mediated protein folding: GroES binds to one end of the GroEL cylinder, which accommodates the protein substrate within its central cavity.

Thomas Langer, Günter Pfeifer, Jörg Martin et al. · The EMBO Journal · 1992 · 417 citations · Full text

, , +16

Dual Function of Protein Confinement in Chaperonin-Assisted Protein Folding

Achim Brinker, Guenther Pfeifer, Michael J. Kerner et al. · Cell · 2001 · 300 citations · Full text

, , +16

Eukaryotic chaperonin CCT stabilizes actin and tubulin folding intermediates in open quasi‐native conformations

Óscar Llorca, Jaime Martín‐Benito, Monica Ritco-Vonsovici et al. · The EMBO Journal · 2000 · 225 citations · Full text

, , +16

1–5 of 37

Authors

156

  1. MH
    Manajit Hayer‐Hartl

    Max Planck Institute of Biochemistry, Germany

    4 publications · 1.2K citations

    4

    h-index

  2. FU
    F. Ulrich Hartl

    Max Planck Institute of Biochemistry, Germany

    3 publications · 1.2K citations

    3

    h-index

  3. AL
    Arthur L. Horwich

    Yale University, United States

    2 publications · 154 citations

    2

    h-index

  4. JZ
    Junjie Zhang

    Texas A&M University, United States

    2 publications · 266 citations

    2

    h-index

  5. NR
    Nicholai R. Douglas

    Stanford University, United States

    2 publications · 266 citations

    2

    h-index

1–5 of 156

Institutions

58

  1. Howard Hughes Medical Institute

    Chevy Chase, United States

    4 h-index

    10 publications

    2.2K citations

  2. Max Planck Institute of Biochemistry

    Martinsried, Germany

    4 h-index

    17 publications

    5.7K citations

  3. Case Western Reserve University

    Cleveland, United States

    3 h-index

    8 publications

    369 citations

  4. Stanford University

    Stanford, United States

    3 h-index

    8 publications

    822 citations

  5. Yale University

    New Haven, United States

    3 h-index

    7 publications

    2.2K citations

  6. Harvard University

    Cambridge, United States

    2 h-index

    7 publications

    256 citations

  7. Max Planck Society

    Munich, Germany

    2 h-index

    5 publications

    513 citations

  8. Institute of Structural and Molecular Biology

    London, United Kingdom

    2 h-index

    5 publications

    478 citations

1–8 of 58

Venues

  1. Journal of Molecular Biology

    JMB · 8 publications · 420 citations

    8

    h-index

  2. Journal of Biological Chemistry

    JBC · 6 publications · 239 citations

    6

    h-index

  3. The EMBO Journal

    3 publications · 790 citations

    3

    h-index

  4. Cell

    2 publications · 966 citations

    2

    h-index

  5. Nature Structural & Molecular Biology

    2 publications · 108 citations

    2

    h-index

1–5