Concepedia

Centromere Instability

Centromere Instability is a biological phenomenon characterized by structural or functional perturbations at the centromere, including aberrant DNA sequences, epigenetic misregulation, or impaired kinetochore assembly, that compromise chromosomal segregation fidelity and contribute to genomic instability.

71

Publications

5.1K

Citations

388

Authors

186

Institutions

Publications per year

2017–2026

23

Parents

Publications

71

Evidence that the MIF2 gene of Saccharomyces cerevisiae encodes a centromere protein with homology to the mammalian centromere protein CENP-C.

Pamela B. Meluh, Douglas Koshland · Molecular Biology of the Cell · 1995 · 428 citations · Full text

, , +17

Tetrameric Structure of Centromeric Nucleosomes in Interphase Drosophila Cells

Yamini Dalal, Hongda Wang, Stuart Lindsay et al. · PLoS Biology · 2007 · 243 citations · Full text

, , +17

DNA methyltransferase 3B (DNMT3B) mutations in ICF syndrome lead to altered epigenetic modifications and aberrant expression of genes regulating development, neurogenesis and immune function

Bilian Jin, Qian Tao, Jinrong Peng et al. · Human Molecular Genetics · 2007 · 236 citations · Full text

, , +17

Inhibition of centromere dynamics by eribulin (E7389) during mitotic metaphase

Tatiana Okouneva, Olga Azarenko, Leslie Wilson et al. · Molecular Cancer Therapeutics · 2008 · 207 citations · Full text

, , +17

Reactivation of an Inactive Centromere Reveals Epigenetic and Structural Components for Centromere Specification in Maize

Fangpu Han, Zhi Gao, James A. Birchler · The Plant Cell · 2009 · 179 citations · Full text

, , +17

1–5 of 71

Authors

388

  1. BA
    Beth A. Sullivan

    Duke University, United States

    3 publications · 165 citations

    3

    h-index

  2. JC
    John Carbon

    University of California, Santa Barbara, United States

    3 publications · 219 citations

    3

    h-index

  3. BF
    Bruce Futcher

    Stony Brook University, United States

    2 publications · 162 citations

    2

    h-index

  4. SL
    Sandra L. Siedlak

    Case Western Reserve University, United States

    2 publications · 38 citations

    2

    h-index

  5. TW
    Therese Wilhelm

    Centre National de la Recherche Scientifique, France

    2 publications · 109 citations

    2

    h-index

1–5 of 388

Institutions

186

  1. Centre National de la Recherche Scientifique

    Paris, France

    4 h-index

    29 publications

    1.5K citations

  2. University of California, Santa Barbara

    Santa Barbara, United States

    3 h-index

    10 publications

    1.2K citations

  3. Case Western Reserve University

    Cleveland, United States

    3 h-index

    5 publications

    91 citations

  4. Center for Cancer Research

    Bethesda, United States

    3 h-index

    14 publications

    1K citations

  5. Duke Medical Center

    Durham, United States

    3 h-index

    7 publications

    771 citations

  6. University of Washington

    Seattle, United States

    3 h-index

    9 publications

    1.3K citations

  7. Fred Hutch Cancer Center

    Seattle, United States

    3 h-index

    4 publications

    573 citations

  8. Howard Hughes Medical Institute

    Chevy Chase, United States

    3 h-index

    4 publications

    552 citations

1–8 of 186

Venues

  1. PLoS Genetics

    5 publications · 297 citations

    5

    h-index

  2. American Journal of Medical Genetics

    4 publications · 203 citations

    4

    h-index

  3. Nucleic Acids Research

    3 publications · 257 citations

    3

    h-index

  4. Genetics

    3 publications · 197 citations

    3

    h-index

  5. Proceedings of the National Academy of Sciences

    PNAS · 3 publications · 379 citations

    3

    h-index

1–5