Concepedia

Cellular Accumulation

Cellular Accumulation is a quantitative measure in cellular drug uptake that denotes the total amount of a drug internalized and retained within cells over time, distinguished from related transport processes by its focus on the net intracellular concentration resultant from uptake, efflux, and metabolic stability.

1.1K

Publications

69.4K

Citations

5.1K

Authors

1.2K

Institutions

Publications per year

2017–2026

154

Parents

Publications

1.1K

Uptake of the anticancer drug cisplatin mediated by the copper transporter Ctr1 in yeast and mammals

Seiko Ishida, Jaekwon Lee, Dennis J. Thiele et al. · Proceedings of the National Academy of Sciences · 2002 · 915 citations · Full text

, , +13

ABCG1 has a critical role in mediating cholesterol efflux to HDL and preventing cellular lipid accumulation

Matthew A. Kennedy, Gabriel Barrera, Kotoka Nakamura et al. · Cell Metabolism · 2005 · 874 citations · Full text

, , +15

Distribution and Tissue Uptake of Poly(ethylene glycol) with Different Molecular Weights after Intravenous Administration to Mice

Tetsuji Yamaoka, Yasuhiko Tabata, Yoshito Ikada · Journal of Pharmaceutical Sciences · 1994 · 734 citations

, , +16

Tonicity-responsive enhancer binding protein, a Rel-like protein that stimulates transcription in response to hypertonicity

Hiroshi Miyakawa, Seung Kyoon Woo, Stephen C. Dahl et al. · Proceedings of the National Academy of Sciences · 1999 · 586 citations

, , +17

Ozone-Sensitive Arabidopsis <i>rcd1</i> Mutant Reveals Opposite Roles for Ethylene and Jasmonate Signaling Pathways in Regulating Superoxide-Dependent Cell Death

Kirk Overmyer, Hannele Tuominen, Reetta Kettunen et al. · The Plant Cell · 2000 · 528 citations · Full text

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1–5 of 1.1K

Authors

5.1K

  1. BK
    Bernhard K. Keppler

    University of Vienna, Austria

    11 publications · 589 citations

    11

    h-index

  2. PM
    Paul M. Tulkens

    UCLouvain, Belgium

    11 publications · 663 citations

    11

    h-index

  3. SB
    Stephen B. Howell

    University of California San Diego, United States

    10 publications · 1K citations

    10

    h-index

  4. FV
    Françoise Van Bambeke

    UCLouvain, Belgium

    10 publications · 585 citations

    10

    h-index

  5. MA
    Michael A. Jakupec

    University of Vienna, Austria

    9 publications · 524 citations

    9

    h-index

1–5 of 5.1K

Institutions

1.2K

  1. Centre National de la Recherche Scientifique

    Paris, France

    22 h-index

    92 publications

    6.3K citations

  2. National Institutes of Health

    Bethesda, United States

    19 h-index

    60 publications

    5K citations

  3. Inserm

    Paris, France

    19 h-index

    74 publications

    4.4K citations

  4. Johns Hopkins University

    Baltimore, United States

    18 h-index

    66 publications

    14.5K citations

  5. UCLouvain

    Louvain-la-Neuve, Belgium

    16 h-index

    61 publications

    3K citations

  6. University of California San Diego

    San Diego, United States

    15 h-index

    58 publications

    4.5K citations

  7. University of Vienna

    Vienna, Austria

    13 h-index

    89 publications

    3.9K citations

  8. Johns Hopkins Medicine

    Baltimore, United States

    13 h-index

    28 publications

    4.6K citations

1–8 of 1.2K

Venues

  1. PubMed

    Repository · 124 publications · 7.7K citations

    47

    h-index

  2. Journal of Biological Chemistry

    JBC · 50 publications · 4.4K citations

    36

    h-index

  3. 20

    h-index

  4. Molecular Pharmacology

    22 publications · 1.5K citations

    18

    h-index

  5. Antimicrobial Agents and Chemotherapy

    AAC · 17 publications · 1.1K citations

    15

    h-index

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