Concepedia

Cell Type-specific Enhancer Activity

Cell Type-Specific Enhancer Activity is a genomic regulatory phenomenon characterized by the selective activation of enhancer elements in a particular cell type, driven by the combinatorial binding of lineage-determining and signal-dependent transcription factors that establish spatial and temporal specificity in gene expression.

893

Publications

71.9K

Citations

4.9K

Authors

896

Institutions

Publications per year

2017–2026

131

Parents

Publications

893

An atlas of active enhancers across human cell types and tissues

Robin Andersson, Claudia Gebhard, Irene Miguel-Escalada et al. · Nature · 2014 · 2.8K citations · Full text

, , +9

A lymphocyte-specific cellular enhancer is located downstream of the joining region in immunoglobulin heavy chain genes

Julian Banerji, Laura Olson, Walter Schaffner · Cell · 1983 · 1.5K citations

, , +14

Genome-Wide Quantitative Enhancer Activity Maps Identified by STARR-seq

Cosmas D. Arnold, Daniel Gerlach, Christoph Stelzer et al. · Science · 2013 · 1.2K citations

, , +15

Identification of a Putative Regulator of Early T Cell Activation Genes

Jeng‐Pyng Shaw, Paul J. Utz, David B. Durand et al. · Science · 1988 · 951 citations

, , +14

Two distinct enhancers with different cell specificities coexist in the regulatory region of polyoma

Philippe Herbomel, Brigitte Bourachot, Moshé Yaniv · Cell · 1984 · 886 citations

, , +10

1–5 of 893

Authors

4.9K

  1. HK
    Hisato Kondoh

    The University of Osaka, Japan

    11 publications · 1K citations

    11

    h-index

  2. RJ
    Raymond J. MacDonald

    The University of Texas Southwestern Medical Center, United States

    10 publications · 429 citations

    10

    h-index

  3. RS
    Ranjan Sen

    National Institute on Aging, United States

    8 publications · 523 citations

    8

    h-index

  4. PN
    Peter N. Cockerill

    University of Birmingham, United Kingdom

    7 publications · 315 citations

    7

    h-index

  5. JM
    Jeffrey M. Leiden

    University of Chicago, United States

    7 publications · 300 citations

    7

    h-index

1–5 of 4.9K

Institutions

896

  1. Howard Hughes Medical Institute

    Chevy Chase, United States

    40 h-index

    149 publications

    18.4K citations

  2. Harvard University

    Cambridge, United States

    37 h-index

    166 publications

    24.3K citations

  3. National Institutes of Health

    Bethesda, United States

    27 h-index

    133 publications

    16.6K citations

  4. University of California, San Francisco

    San Francisco, United States

    24 h-index

    93 publications

    9.2K citations

  5. Centre National de la Recherche Scientifique

    Paris, France

    20 h-index

    113 publications

    7K citations

  6. Dana-Farber Cancer Institute

    Boston, United States

    19 h-index

    83 publications

    10.5K citations

  7. Massachusetts Institute of Technology

    Cambridge, United States

    19 h-index

    73 publications

    12.6K citations

  8. The University of Texas Southwestern Medical Center

    Dallas, United States

    18 h-index

    74 publications

    9.2K citations

1–8 of 896

Venues

  1. Molecular and Cellular Biology

    MCB · 165 publications · 11.2K citations

    59

    h-index

  2. Journal of Biological Chemistry

    JBC · 95 publications · 5.4K citations

    47

    h-index

  3. Nucleic Acids Research

    67 publications · 3.8K citations

    37

    h-index

  4. Proceedings of the National Academy of Sciences

    PNAS · 40 publications · 5.1K citations

    34

    h-index

  5. The Journal of Immunology

    JI · 40 publications · 1.6K citations

    26

    h-index

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