Concepedia

Cell Therapy Dose Optimization

Cell Therapy Dose Optimization is a methodological framework in cell-based therapeutics that systematically determines the optimal dosage of viable cells to maximize therapeutic efficacy while minimizing adverse effects through iterative preclinical and clinical evaluation.

53

Publications

2.5K

Citations

508

Authors

242

Institutions

Publications per year

2017–2026

21

Parents

Publications

53

Long-Term Outcomes From a Randomized Dose Optimization Study of Chimeric Antigen Receptor Modified T Cells in Relapsed Chronic Lymphocytic Leukemia

Noelle V. Frey, Saar Gill, Elizabeth O. Hexner et al. · Journal of Clinical Oncology · 2020 · 185 citations · Full text

, , +17

Donor lymphocyte infusion for relapsed chronic myelogenous leukemia: prognostic relevance of the initial cell dose

Cesare Guglielmi · Blood · 2002 · 185 citations · Full text

, , +17

How to design preclinical studies in nanomedicine and cell therapy to maximize the prospects of clinical translation

John P. A. Ioannidis, Betty Y.S. Kim · Nature Biomedical Engineering · 2018 · 156 citations · Full text

, , +16

Stem cell transplantation in the normal nonmyeloablated host: relationship between cell dose, schedule, and engraftment.

SS Rao, Peters So, Crittenden Rb et al. · PubMed · 1997 · 133 citations

, , +16

A dose response analysis of a specific bone marrow concentrate treatment protocol for knee osteoarthritis

Christopher J. Centeno, Hasan Al‐Sayegh, Jamil Bashir et al. · BMC Musculoskeletal Disorders · 2015 · 107 citations · Full text

, , +17

1–5 of 53

Authors

508

  1. YJ
    Yuan Ji

    Endeavor Health, United States

    3 publications · 97 citations

    3

    h-index

  2. PR
    Paul R. Sanberg

    University of South Florida, United States

    3 publications · 170 citations

    3

    h-index

  3. AW
    Alison W. Loren

    University of Pennsylvania, United States

    2 publications · 218 citations

    2

    h-index

  4. CH
    Carl H. June

    University of Pennsylvania, United States

    2 publications · 218 citations

    2

    h-index

  5. DL
    David L. Porter

    University of Pennsylvania, United States

    2 publications · 218 citations

    2

    h-index

1–5 of 508

Institutions

242

  1. University of South Florida

    Tampa, United States

    4 h-index

    15 publications

    1K citations

  2. Fred Hutch Cancer Center

    Seattle, United States

    3 h-index

    12 publications

    308 citations

  3. Baylor College of Medicine

    Houston, United States

    3 h-index

    3 publications

    108 citations

  4. University College London

    London, United Kingdom

    2 h-index

    3 publications

    130 citations

  5. Uppsala University Hospital

    Uppsala, Sweden

    2 h-index

    2 publications

    69 citations

  6. Tianjin Medical University General Hospital

    Tianjin, China

    2 h-index

    2 publications

    69 citations

  7. First Affiliated Hospital of Soochow University

    Suzhou, China

    2 h-index

    2 publications

    69 citations

  8. Wake Forest University

    Winston-Salem, United States

    2 h-index

    2 publications

    22 citations

1–8 of 242

Venues

  1. Journal of Clinical Oncology

    5 publications · 287 citations

    5

    h-index

  2. Blood

    4 publications · 393 citations

    4

    h-index

  3. PubMed

    Repository · 3 publications · 229 citations

    3

    h-index

  4. Bone Marrow Transplantation

    3 publications · 94 citations

    3

    h-index

  5. Cell Transplantation

    2 publications · 78 citations

    2

    h-index

1–5