Concepedia

Cap-independent Initiation

Cap-Independent Initiation is a mechanism of translation initiation in which ribosomes are recruited to the mRNA without reliance on the 5' cap structure, typically mediated by internal ribosome entry sites (IRES) or other cap-independent regulatory elements.

66

Publications

7.4K

Citations

242

Authors

103

Institutions

Publications per year

2017–2026

8

Parents

Publications

66

5′ UTR m6A Promotes Cap-Independent Translation

Kate D. Meyer, Deepak P. Patil, Jun Zhou et al. · Cell · 2015 · 1.8K citations · Full text

, , +14

Initiation of protein synthesis by internal entry of ribosomes into the 5' nontranslated region of encephalomyocarditis virus RNA in vivo

Sung Key Jang, Monique V. Davies, Randal J. Kaufman et al. · Journal of Virology · 1989 · 418 citations · Full text

, , +17

Dominant negative mutants of mammalian translation initiation factor eIF‐4A define a critical role for eIF‐4F in cap‐dependent and cap‐independent initiation of translation.

Arnim Pause, Nathalie Méthot, Yuri V. Svitkin et al. · The EMBO Journal · 1994 · 393 citations · Full text

, , +15

Prokaryotic-like cis elements in the cap-independent internal initiation of translation on picornavirus RNA

Evgeny V. Pilipenko, Anatoly P. Gmyl, Svetlana V. Maslova et al. · Cell · 1992 · 275 citations

, , +16

The La antigen binds 5′ noncoding region of the hepatitis C virus RNA in the context of the initiator AUG codon and stimulates internal ribosome entry site-mediated translation

Naushad Ali, Aleem Siddiqui · Proceedings of the National Academy of Sciences · 1997 · 270 citations

, , +16

1–5 of 66

Authors

242

  1. NS
    Nahum Sonenberg

    McGill University, Canada

    3 publications · 548 citations

    3

    h-index

  2. WC
    William C. Merrick

    Case Western Reserve University, United States

    3 publications · 513 citations

    3

    h-index

  3. BL
    Bert L. Semler

    University of California, Irvine, United States

    3 publications · 322 citations

    3

    h-index

  4. MV
    Monique V. Davies

    Acceleron Pharma (United States), United States

    2 publications · 500 citations

    2

    h-index

  5. KP
    Karla Pino

    Pontificia Universidad Católica de Chile, Chile

    2 publications · 53 citations

    2

    h-index

1–5 of 242

Institutions

103

  1. McGill University

    Montreal, Canada

    5 h-index

    13 publications

    2.5K citations

  2. University of Cambridge

    Cambridge, United Kingdom

    3 h-index

    13 publications

    1.1K citations

  3. University of Colorado Health

    Aurora, United States

    3 h-index

    5 publications

    1.1K citations

  4. Chumakov Institute of Poliomyelitis and Viral Encephalitides

    Moscow, Russia

    3 h-index

    15 publications

    2K citations

  5. Lomonosov Moscow State University

    Moscow, Russia

    3 h-index

    9 publications

    567 citations

  6. University of California, Irvine

    Irvine, United States

    3 h-index

    10 publications

    1.4K citations

  7. Biotechnology and Biological Sciences Research Council

    Swindon, United Kingdom

    2 h-index

    4 publications

    352 citations

  8. Baylor College of Medicine

    Houston, United States

    2 h-index

    7 publications

    841 citations

1–8 of 103

Venues

  1. Journal of Virology

    JVI · 10 publications · 1.3K citations

    10

    h-index

  2. Journal of Biological Chemistry

    JBC · 7 publications · 560 citations

    7

    h-index

  3. RNA

    6 publications · 410 citations

    6

    h-index

  4. Nucleic Acids Research

    3 publications · 239 citations

    3

    h-index

  5. Journal of Molecular Biology

    JMB · 2 publications · 277 citations

    2

    h-index

1–5