Concepedia

Cap-binding Protein Complex

The Cap-Binding Protein Complex is a eukaryotic translation initiation factor complex that, by specifically recognizing and binding to the 7-methylguanosine cap structure at the 5′ end of messenger RNA, facilitates ribosome recruitment and enhances translational efficiency.

324

Publications

31.3K

Citations

1.3K

Authors

374

Institutions

Publications per year

2017–2026

49

Variants

Eif4fEukaryotic Initiation Factor 4F

Parents

Publications

324

RAFT1 phosphorylation of the translational regulators p70 S6 kinase and 4E-BP1

Patrick E. Burnett, Roxanne K. Barrow, Noam A. Cohen et al. · Proceedings of the National Academy of Sciences · 1998 · 1.1K citations

, , +14

Crystal Structure of a CAP-DNA Complex: the DNA Is Bent by 90°

Steve C. Schultz, George C. Shields, Thomas A. Steitz · Science · 1991 · 1.1K citations

, , +15

Malignant transformation by a eukaryotic initiation factor subunit that binds to mRNA 5' cap

A. Lazaris-Karatzas, Kathleen S. Montine, Nahum Sonenberg · Nature · 1990 · 959 citations

, , +14

The cap and poly(A) tail function synergistically to regulate mRNA translational efficiency.

Daniel Gallie · Genes & Development · 1991 · 858 citations · Full text

, , +17

Cocrystal Structure of the Messenger RNA 5′ Cap-Binding Protein (eIF4E) Bound to 7-methyl-GDP

Joseph Marcotrigiano, Anne‐Claude Gingras, Nahum Sonenberg et al. · Cell · 1997 · 680 citations · Full text

, , +16

1–5 of 324

Authors

1.3K

  1. NS
    Nahum Sonenberg

    McGill University, Canada

    40 publications · 6.6K citations

    34

    h-index

  2. ED
    Edward Darżynkiewicz

    University of Warsaw, Poland

    12 publications · 1.1K citations

    12

    h-index

  3. IE
    Isaac Edery

    Rutgers, The State University of New Jersey, United States

    11 publications · 2.1K citations

    11

    h-index

  4. DE
    D Etchison

    University of California, Davis, United States

    10 publications · 1.1K citations

    10

    h-index

  5. RJ
    Robert J. Schneider

    New York University, United States

    9 publications · 818 citations

    9

    h-index

1–5 of 1.3K

Institutions

374

  1. McGill University

    Montreal, Canada

    31 h-index

    126 publications

    28.6K citations

  2. University of Warsaw

    Warsaw, Poland

    14 h-index

    53 publications

    4.2K citations

  3. Howard Hughes Medical Institute

    Chevy Chase, United States

    12 h-index

    24 publications

    3.5K citations

  4. European Molecular Biology Laboratory

    Heidelberg, Germany

    11 h-index

    29 publications

    4.1K citations

  5. New York University

    New York, United States

    10 h-index

    25 publications

    2.2K citations

  6. Rutgers, The State University of New Jersey

    New Brunswick, United States

    9 h-index

    31 publications

    2.7K citations

  7. Yale University

    New Haven, United States

    9 h-index

    20 publications

    5K citations

  8. Adam Mickiewicz University in Poznań

    Poznan, Poland

    8 h-index

    33 publications

    1.6K citations

1–8 of 374

Venues

  1. Journal of Biological Chemistry

    JBC · 43 publications · 3.6K citations

    31

    h-index

  2. Journal of Virology

    JVI · 29 publications · 2.4K citations

    27

    h-index

  3. Nucleic Acids Research

    28 publications · 1.6K citations

    21

    h-index

  4. Proceedings of the National Academy of Sciences

    PNAS · 20 publications · 3.6K citations

    20

    h-index

  5. Molecular and Cellular Biology

    MCB · 19 publications · 2.9K citations

    19

    h-index

1–5