Concepedia

C-end Rule Pathway

The C-End Rule Pathway is a ubiquitin ligase recognition mechanism in protein degradation that specifies substrate targeting through C-terminal amino acid sequences, distinguishing it from other degron pathways by its exclusive dependence on terminal residue identity for ligase binding.

9

Publications

2K

Citations

68

Authors

35

Institutions

Publications per year

2017–2026

4

Parents

Publications

9

Neuropilin-1 is a host factor for SARS-CoV-2 infection

James L. Daly, Boris Simonetti, Katja Klein et al. · Science · 2020 · 1.4K citations · Full text

, , +17

Neuropilin-1 is a host factor for SARS-CoV-2 infection

James L. Daly, Boris Simonetti, Carlos Antón-Plágaro et al. · bioRxiv (Cold Spring Harbor Laboratory) · 2020 · 140 citations · Full text

, , +17

Sequence dependence of C-end rule peptides in binding and activation of neuropilin-1 receptor

David Zanuy, Rohith Kotla, Ruth Nussinov et al. · Journal of Structural Biology · 2013 · 123 citations · Full text

, , +16

Aminoacyl-transferases and the N-end rule pathway of prokaryotic/eukaryotic specificity in a human pathogen

Emmanuelle Graciet, Ronggui Hu, Konstantin Piatkov et al. · Proceedings of the National Academy of Sciences · 2006 · 95 citations · Full text

, , +17

Neuropilin-1 and heparan sulfate proteoglycans cooperate in cellular uptake of nanoparticles functionalized by cationic cell-penetrating peptides

Hong‐Bo Pang, Gary B. Braun, Erkki Ruoslahti · Science Advances · 2015 · 85 citations · Full text

, , +15

1–5 of 9

Authors

68

  1. TT
    Tambet Teesalu

    University of Tartu, Estonia

    3 publications · 1.6K citations

    3

    h-index

  2. RB
    Richard B. Sessions

    University of Bristol, United Kingdom

    2 publications · 1.5K citations

    2

    h-index

  3. AH
    Ari Helenius

    Yale University, United States

    2 publications · 1.5K citations

    2

    h-index

  4. UF
    Urs F. Greber

    University of Zurich, Switzerland

    2 publications · 1.5K citations

    2

    h-index

  5. DA
    David A. Matthews

    University of Bristol, United Kingdom

    2 publications · 1.5K citations

    2

    h-index

1–5 of 68

Institutions

35

  1. Finland University

    Helsinki, Finland

    2 h-index

    2 publications

    1.5K citations

  2. University of Helsinki

    Helsinki, Finland

    2 h-index

    2 publications

    1.5K citations

  3. Sanford Burnham Prebys Medical Discovery Institute

    La Jolla, United States

    2 h-index

    5 publications

    501 citations

  4. Institute for Molecular Medicine Finland

    Helsinki, Finland

    2 h-index

    2 publications

    1.5K citations

  5. ETH Zurich

    Zurich, Switzerland

    2 h-index

    2 publications

    1.5K citations

  6. University of Tartu

    Tartu, Estonia

    2 h-index

    4 publications

    3K citations

  7. University of Bristol

    Bristol, United Kingdom

    2 h-index

    22 publications

    16.5K citations

  8. University of Zurich

    Zurich, Switzerland

    2 h-index

    4 publications

    3K citations

1–8 of 35

Venues

  1. Proceedings of the National Academy of Sciences

    PNAS · 1 publications · 95 citations

    1

    h-index

  2. Journal of Structural Biology

    1 publications · 123 citations

    1

    h-index

  3. Science Advances

    1 publications · 85 citations

    1

    h-index

  4. Journal of Biological Chemistry

    JBC · 1 publications · 35 citations

    1

    h-index

  5. Acta Pharmaceutica Sinica B

    APSB · 1 publications · 30 citations

    1

    h-index

1–5