Concepedia

Bottom-up Proteomics Quantification

Bottom-Up Proteomics Quantification is a methodological approach in protein quantification that involves the enzymatic digestion of proteins into peptides prior to mass spectrometric analysis, enabling indirect quantification of proteins through peptide-level measurements.

170

Publications

26.5K

Citations

949

Authors

351

Institutions

Publications per year

2017–2026

94

Parents

Publications

170

MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification

Jürgen Cox, Matthias Mann · Nature Biotechnology · 2008 · 15.7K citations

, , +15

Absolute Quantification of Proteins by LCMSE

Jeffrey C. Silva, M. V. Gorenstein, Guozhong Li et al. · Molecular & Cellular Proteomics · 2005 · 1.6K citations · Full text

, , +12

Multiplexed absolute quantification in proteomics using artificial QCAT proteins of concatenated signature peptides

Robert J. Beynon, Mary K. Doherty, Julie M. Pratt et al. · Nature Methods · 2005 · 466 citations

, , +15

Comparison of different depletion strategies for improved resolution in proteomic analysis of human serum samples

Karin Björhall, Tasso Miliotis, Pia Davidsson · PROTEOMICS · 2005 · 385 citations · Full text

, , +16

Multiplexed absolute quantification for proteomics using concatenated signature peptides encoded by QconCAT genes

Julie M. Pratt, Deborah M. Simpson, Mary K. Doherty et al. · Nature Protocols · 2006 · 375 citations

, , +14

1–5 of 170

Authors

949

  1. RS
    Richard Smith

    Pacific Northwest National Laboratory, United States

    6 publications · 658 citations

    6

    h-index

  2. NL
    Neil L. Kelleher

    Northwestern University, United States

    5 publications · 325 citations

    5

    h-index

  3. JR
    Jacek R. Wiśniewski

    Max Planck Institute of Biochemistry, Germany

    4 publications · 262 citations

    4

    h-index

  4. MJ
    Matthew J. Ellis

    Washington University in St. Louis, United States

    3 publications · 223 citations

    3

    h-index

  5. JJ
    Joshua J. Coon

    University of Wisconsin–Madison, United States

    3 publications · 351 citations

    3

    h-index

1–5 of 949

Institutions

351

  1. University of Wisconsin–Madison

    Madison, United States

    8 h-index

    34 publications

    1.8K citations

  2. Pacific Northwest National Laboratory

    Richland, United States

    7 h-index

    55 publications

    5.2K citations

  3. Centre National de la Recherche Scientifique

    Paris, France

    6 h-index

    13 publications

    399 citations

  4. Inserm

    Paris, France

    6 h-index

    11 publications

    326 citations

  5. University of Manchester

    Manchester, United Kingdom

    5 h-index

    13 publications

    1.3K citations

  6. University of Pennsylvania

    Philadelphia, United States

    5 h-index

    24 publications

    812 citations

  7. Harvard University

    Cambridge, United States

    5 h-index

    12 publications

    1.4K citations

  8. Max Planck Institute of Biochemistry

    Martinsried, Germany

    5 h-index

    6 publications

    31.7K citations

1–8 of 351

Venues

  1. Analytical Chemistry

    23 publications · 1.2K citations

    19

    h-index

  2. Journal of Proteome Research

    JPR · 24 publications · 1.3K citations

    19

    h-index

  3. Molecular & Cellular Proteomics

    MCP · 12 publications · 2.3K citations

    12

    h-index

  4. PROTEOMICS

    8 publications · 781 citations

    8

    h-index

  5. Journal of the American Society for Mass Spectrometry

    JASMS · 7 publications · 226 citations

    7

    h-index

1–5