Concepedia

Bmpr2 Signaling

Bmpr2 Signaling is a molecular signaling pathway within the bone morphogenetic protein signaling cascade that specifically mediates cellular responses to BMP ligands through the activation and regulation of the BMP receptor type II (BMPR2), distinguishing it by its unique dependence on BMPR2 kinase activity and its role in downstream SMAD and non-SMAD signal transduction.

434

Publications

35.1K

Citations

3K

Authors

844

Institutions

Publications per year

2017–2026

150

Variants

Bmpr2 Signaling Pathway

Parents

Publications

434

Stimulation of Bone Formation in Vitro and in Rodents by Statins

Gregory R. Mundy, R.J. Burriss Garrett, S. E. Harris et al. · Science · 1999 · 1.8K citations

, , +16

BMP2 activity, although dispensable for bone formation, is required for the initiation of fracture healing

Kunikazu Tsuji, Amitabha Bandyopadhyay, Brian D. Harfe et al. · Nature Genetics · 2006 · 817 citations

, , +15

MADR1, a MAD-Related Protein That Functions in BMP2 Signaling Pathways

Pamela A. Hoodless, Theo Haerry, Shirin Abdollah et al. · Cell · 1996 · 706 citations · Full text

, , +8

Primary Pulmonary Hypertension Is Associated With Reduced Pulmonary Vascular Expression of Type II Bone Morphogenetic Protein Receptor

Carl Atkinson, Susan Stewart, Paul D. Upton et al. · Circulation · 2002 · 684 citations · Full text

, , +15

Endothelial-to-Mesenchymal Transition in Pulmonary Hypertension

Benoît Ranchoux, Fabrice Antigny, Catherine Rücker‐Martin et al. · Circulation · 2015 · 572 citations · Full text

, , +14

1–5 of 434

Authors

3K

  1. JW
    James West

    Vanderbilt University Medical Center, United States

    26 publications · 1.9K citations

    23

    h-index

  2. NW
    Nicholas W. Morrell

    University of Cambridge, United Kingdom

    30 publications · 3.7K citations

    23

    h-index

  3. JE
    James E. Loyd

    Vanderbilt University, United States

    16 publications · 1.5K citations

    16

    h-index

  4. RC
    Richard C. Trembath

    King's College London, United Kingdom

    14 publications · 3.4K citations

    14

    h-index

  5. MH
    Marc Humbert

    Inserm, France

    14 publications · 2.9K citations

    14

    h-index

1–5 of 3K

Institutions

844

  1. Vanderbilt University Medical Center

    Nashville, United States

    23 h-index

    144 publications

    12.3K citations

  2. University of Cambridge

    Cambridge, United Kingdom

    21 h-index

    121 publications

    15.8K citations

  3. Vanderbilt University

    Nashville, United States

    18 h-index

    90 publications

    5.3K citations

  4. Inserm

    Paris, France

    15 h-index

    107 publications

    19K citations

  5. Addenbrooke's Hospital

    Cambridge, United Kingdom

    14 h-index

    60 publications

    11.1K citations

  6. Papworth Hospital

    Cambridge, United Kingdom

    14 h-index

    83 publications

    15.6K citations

  7. Stanford University

    Stanford, United States

    14 h-index

    95 publications

    13.7K citations

  8. Harvard University

    Cambridge, United States

    14 h-index

    77 publications

    11.8K citations

1–8 of 844

Venues

  1. Bone

    23 publications · 2K citations

    22

    h-index

  2. Pulmonary Circulation

    17 publications · 488 citations

    14

    h-index

  3. Circulation

    14 publications · 3K citations

    14

    h-index

  4. American Journal of Respiratory and Critical Care Medicine

    AJRCCM · 14 publications · 1.2K citations

    13

    h-index

  5. Journal of Biological Chemistry

    JBC · 13 publications · 1.6K citations

    12

    h-index

1–5