Concepedia

Biocontainment Systems

Biocontainment System is a biological safeguard framework designed to prevent the unintended spread or persistence of genetically modified organisms in the environment by implementing genetic, chemical, or physical constraints that distinguish it from general containment strategies through its reliance on orthogonal biochemical mechanisms.

58

Publications

3.4K

Citations

448

Authors

155

Institutions

Publications per year

2017–2026

28

Parents

Publications

58

BioContainers: an open-source and community-driven framework for software standardization

Felipe da Veiga Leprevost, Björn Grüning, Saulo Aflitos et al. · Bioinformatics · 2017 · 839 citations · Full text

, , +11

Next-generation biocontainment systems for engineered organisms

Jeong Wook Lee, Clement T. Y. Chan, Shimyn Slomovic et al. · Nature Chemical Biology · 2018 · 266 citations · Full text

, , +7

Genetically stable CRISPR-based kill switches for engineered microbes

Austin G. Rottinghaus, Aura Ferreiro, Skye R. S. Fishbein et al. · Nature Communications · 2022 · 256 citations · Full text

, , +14

Preparing synthetic biology for the world

Gerd Moe-Behrens, Rene Davis, Karmella A. Haynes · Frontiers in Microbiology · 2013 · 160 citations · Full text

, , +7

Multilayered genetic safeguards limit growth of microorganisms to defined environments

Ryan R. Gallagher, Jaymin R. Patel, Alexander L. Interiano et al. · Nucleic Acids Research · 2015 · 159 citations · Full text

, , +16

1–5 of 58

Authors

448

  1. LS
    Lauren Sauer

    Johns Hopkins University, United States

    5 publications · 99 citations

    5

    h-index

  2. BT
    Brian T. Garibaldi

    Johns Hopkins University, United States

    4 publications · 86 citations

    4

    h-index

  3. LL
    Lisa L. Maragakis

    Johns Hopkins University, United States

    3 publications · 74 citations

    3

    h-index

  4. CS
    Colleen S. Kraft

    Emory University, United States

    3 publications · 59 citations

    3

    h-index

  5. JB
    Joan B. Geisbert

    The University of Texas Medical Branch at Galveston, United States

    2 publications · 199 citations

    2

    h-index

1–5 of 448

Institutions

155

  1. Johns Hopkins University

    Baltimore, United States

    6 h-index

    48 publications

    1.9K citations

  2. Nebraska Medical Center

    Omaha, United States

    5 h-index

    19 publications

    804 citations

  3. University of Nebraska Medical Center

    Omaha, United States

    4 h-index

    18 publications

    974 citations

  4. Johns Hopkins Hospital

    Baltimore, United States

    4 h-index

    14 publications

    504 citations

  5. Johns Hopkins Medicine

    Baltimore, United States

    4 h-index

    35 publications

    1.6K citations

  6. University of Minnesota

    Minneapolis, United States

    3 h-index

    4 publications

    194 citations

  7. United States Department of Agriculture

    Washington, United States

    3 h-index

    9 publications

    599 citations

  8. Emory University

    Atlanta, United States

    3 h-index

    8 publications

    170 citations

1–8 of 155

Venues

  1. Nature Communications

    4 publications · 382 citations

    4

    h-index

  2. Health Security

    4 publications · 52 citations

    4

    h-index

  3. Scientific Reports

    3 publications · 92 citations

    3

    h-index

  4. Journal of Virological Methods

    2 publications · 43 citations

    2

    h-index

  5. Emerging infectious diseases

    EID · 2 publications · 147 citations

    2

    h-index

1–5