Concepedia

Beta-sheet Mimics

Beta-Sheet Mimics is a peptidomimetic design strategy that adopts synthetic scaffolds or non-peptidic frameworks to structurally and functionally emulate the interstrand hydrogen-bonded architecture of natural β-sheets while enhancing metabolic stability and bioavailability.

137

Publications

6.1K

Citations

525

Authors

170

Institutions

Publications per year

2017–2026

14

Variants

Beta-sheet Mimetics

Parents

Publications

137

β-Peptidic Peptidomimetics

Dieter Seebàch, James Gardiner · Accounts of Chemical Research · 2008 · 700 citations

, , +15

Amyloid β-sheet mimics that antagonize protein aggregation and reduce amyloid toxicity

Pin‐Nan Cheng, Cong Liu, Minglei Zhao et al. · Nature Chemistry · 2012 · 242 citations · Full text

, , +16

Use of a Designed Triple-Stranded Antiparallel β-Sheet To Probe β-Sheet Cooperativity in Aqueous Solution

Heather L. Schenck, Samuel H. Gellman · Journal of the American Chemical Society · 1998 · 184 citations

, , +6

Construction and Design of β-Sheets

Catherine K. Smith, Lynne Regan · Accounts of Chemical Research · 1997 · 181 citations

, , +12

Simultaneous Solid-Phase Synthesis of .beta.-Turn Mimetics Incorporating Side-Chain Functionality

Alex A. Virgilio, Jonathan A. Ellman · Journal of the American Chemical Society · 1994 · 132 citations

, , +6

1–5 of 137

Authors

525

  1. JS
    James S. Nowick

    University of California, Irvine, United States

    13 publications · 923 citations

    13

    h-index

  2. EM
    Eric M. Smith

    The University of Texas Medical Branch at Galveston, United States

    5 publications · 303 citations

    5

    h-index

  3. AD
    Andrew D. Hamilton

    Yale University, United States

    4 publications · 196 citations

    4

    h-index

  4. HK
    Heinz‐Bernhard Kraatz

    University of Toronto, Canada

    4 publications · 198 citations

    4

    h-index

  5. DL
    Darren L. Holmes

    University of California, Irvine, United States

    4 publications · 256 citations

    4

    h-index

1–5 of 525

Institutions

170

  1. University of California, Irvine

    Irvine, United States

    14 h-index

    54 publications

    3.8K citations

  2. Centre National de la Recherche Scientifique

    Paris, France

    9 h-index

    46 publications

    1.1K citations

  3. Texas A&M University

    College Station, United States

    5 h-index

    10 publications

    194 citations

  4. New York University

    New York, United States

    5 h-index

    14 publications

    672 citations

  5. Philipps University of Marburg

    Marburg, Germany

    4 h-index

    11 publications

    307 citations

  6. University of Wisconsin–Madison

    Madison, United States

    4 h-index

    10 publications

    560 citations

  7. Western University

    London, Canada

    4 h-index

    7 publications

    296 citations

  8. Sorbonne Université

    Paris, France

    4 h-index

    7 publications

    149 citations

1–8 of 170

Venues

  1. Journal of the American Chemical Society

    JACS · 21 publications · 1.5K citations

    20

    h-index

  2. The Journal of Organic Chemistry

    JOC · 15 publications · 455 citations

    13

    h-index

  3. Tetrahedron Letters

    10 publications · 266 citations

    10

    h-index

  4. Organic Letters

    OL · 8 publications · 227 citations

    8

    h-index

  5. Angewandte Chemie International Edition

    6 publications · 234 citations

    6

    h-index

1–5