Concepedia

Bayesian Group Sequential Design

Bayesian Group Sequential Design is a statistical methodology for clinical trials that belongs to the class of group sequential designs and is distinguished by its incorporation of Bayesian inference to evaluate accumulating data at predefined interim analyses, allowing for adaptive decision-making regarding trial continuation, early stopping for efficacy or futility, and parameter estimation using prior and posterior probability distributions.

39

Publications

2.8K

Citations

160

Authors

86

Institutions

Publications per year

2017–2026

11

Parents

Publications

39

Acute Stroke Therapy by Inhibition of Neutrophils (ASTIN)

Michael Krams, Kennedy R. Lees, Werner Hacke et al. · Stroke · 2003 · 429 citations

, , +17

Bayesian Approaches to Clinical Trials and Health-Care Evaluation

Mark A. Best · Journal of the Royal Statistical Society Series A (Statistics in Society) · 2004 · 314 citations · Full text

, , +13

Self-designing clinical trials

Lloyd D. Fisher · Statistics in Medicine · 1998 · 292 citations

, , +14

Randomized Phase IIB Trial of Proton Beam Therapy Versus Intensity-Modulated Radiation Therapy for Locally Advanced Esophageal Cancer

Steven H. Lin, Brian P. Hobbs, Vivek Verma et al. · Journal of Clinical Oncology · 2020 · 262 citations · Full text

, , +17

Comparison of Bayesian with group sequential methods for monitoring clinical trials

Laurence S. Freedman, David J. Spiegelhalter · Controlled Clinical Trials · 1989 · 127 citations

, , +12

1–5 of 39

Authors

160

  1. DA
    Donald A. Berry

    The University of Texas MD Anderson Cancer Center, United States

    4 publications · 196 citations

    4

    h-index

  2. RL
    Roger Lewis

    UCLA Medical Center, United States

    3 publications · 164 citations

    3

    h-index

  3. BP
    Brian P. Hobbs

    The University of Texas MD Anderson Cancer Center, United States

    2 publications · 298 citations

    2

    h-index

  4. SH
    Steven H. Lin

    The University of Texas MD Anderson Cancer Center, United States

    2 publications · 298 citations

    2

    h-index

  5. YY
    Ying Yuan

    The University of Texas MD Anderson Cancer Center, United States

    2 publications · 131 citations

    2

    h-index

1–5 of 160

Institutions

86

  1. The University of Texas MD Anderson Cancer Center

    Houston, United States

    5 h-index

    29 publications

    6.1K citations

  2. Duke University

    Durham, United States

    4 h-index

    7 publications

    268 citations

  3. Decision Sciences (United States)

    Fort Walton Beach, United States

    4 h-index

    5 publications

    219 citations

  4. UCLA Medical Center

    Santa Monica, United States

    3 h-index

    3 publications

    164 citations

  5. National Institutes of Health

    Bethesda, United States

    3 h-index

    3 publications

    159 citations

  6. Harbor–UCLA Medical Center

    Torrance, United States

    3 h-index

    4 publications

    208 citations

  7. MRC Biostatistics Unit

    Cambridge, United Kingdom

    3 h-index

    3 publications

    264 citations

  8. Fudan University

    Shanghai, China

    2 h-index

    4 publications

    70 citations

1–8 of 86

Venues

  1. Statistics in Medicine

    7 publications · 550 citations

    7

    h-index

  2. 3

    h-index

  3. Statistical Methods in Medical Research

    2 publications · 29 citations

    2

    h-index

  4. 2

    h-index

  5. Controlled Clinical Trials

    2 publications · 149 citations

    2

    h-index

1–5