Concepedia

Backbone Refinement

Backbone Refinement is a computational optimization method within homology modeling that specifically improves the accuracy of the predicted protein structure by adjusting the polypeptide backbone conformation while preserving side-chain connectivity and stereochemical constraints.

109

Publications

10.5K

Citations

419

Authors

184

Institutions

Publications per year

2017–2026

17

Parents

Publications

109

Automated protein model building combined with iterative structure refinement.

Anastassis Perrakis, Richard J. Morris, Victor S. Lamzin · Nature Structural Biology · 1999 · 2.4K citations

, , +11

A Smoothed Backbone-Dependent Rotamer Library for Proteins Derived from Adaptive Kernel Density Estimates and Regressions

Maxim V. Shapovalov, Roland L. Dunbrack · Structure · 2011 · 1.1K citations

, , +15

Macromolecular TLS Refinement in REFMAC at Moderate Resolutions

Martyn Winn, Garib N. Murshudov, Miroslav Z. Papiz · Methods in enzymology on CD-ROM/Methods in enzymology · 2003 · 806 citations

, , +11

Automated main-chain model building by template matching and iterative fragment extension

Thomas C. Terwilliger · Acta Crystallographica Section D Biological Crystallography · 2002 · 582 citations · Full text

, , +15

High‐accuracy protein structure prediction in <scp>CASP14</scp>

Joana Pereira, Adam J. Simpkin, Marcus D. Hartmann et al. · Proteins Structure Function and Bioinformatics · 2021 · 338 citations · Full text

, , +10

1–5 of 109

Authors

419

  1. WC
    Wah Chiu

    Baylor College of Medicine, United States

    3 publications · 448 citations

    3

    h-index

  2. HA
    Harold A. Scheraga

    Cornell University, United States

    3 publications · 235 citations

    3

    h-index

  3. AK
    Andriy Kryshtafovych

    University of California, Davis, United States

    3 publications · 130 citations

    3

    h-index

  4. BK
    Brian Kuhlman

    University of North Carolina at Chapel Hill, United States

    3 publications · 122 citations

    3

    h-index

  5. JK
    John Kuszewski

    National Institutes of Health, United States

    3 publications · 345 citations

    3

    h-index

1–5 of 419

Institutions

184

  1. Scripps Research Institute

    San Diego, United States

    4 h-index

    14 publications

    460 citations

  2. ETH Zurich

    Zurich, Switzerland

    4 h-index

    8 publications

    294 citations

  3. University of North Carolina at Chapel Hill

    Chapel Hill, United States

    4 h-index

    13 publications

    436 citations

  4. National Institutes of Health

    Bethesda, United States

    4 h-index

    14 publications

    1.4K citations

  5. Harvard University

    Cambridge, United States

    3 h-index

    4 publications

    147 citations

  6. National Institute of Diabetes and Digestive and Kidney Diseases

    Bethesda, United States

    3 h-index

    5 publications

    404 citations

  7. New York University

    New York, United States

    3 h-index

    20 publications

    1.4K citations

  8. University of California, San Francisco

    San Francisco, United States

    3 h-index

    8 publications

    580 citations

1–8 of 184

Venues

  1. Proteins Structure Function and Bioinformatics

    17 publications · 1.6K citations

    17

    h-index

  2. Journal of Biomolecular NMR

    16 publications · 592 citations

    13

    h-index

  3. Biomolecular NMR Assignments

    8 publications · 130 citations

    8

    h-index

  4. Journal of Molecular Biology

    JMB · 4 publications · 511 citations

    4

    h-index

  5. Journal of Magnetic Resonance

    JMR · 4 publications · 72 citations

    4

    h-index

1–5