Concepedia

Backbone Reconstruction

Backbone Reconstruction is a computational method in ab initio structure prediction that specifically entails the determination of the three-dimensional conformation of a protein's polypeptide backbone from its amino acid sequence, distinguishing itself from full-atom modeling by focusing exclusively on the spatial arrangement of backbone atoms (N, Cα, C) to enable subsequent side-chain placement and refinement.

87

Publications

5.5K

Citations

366

Authors

178

Institutions

Publications per year

2017–2026

7

Parents

Publications

87

Automated main-chain model building by template matching and iterative fragment extension

Thomas C. Terwilliger · Acta Crystallographica Section D Biological Crystallography · 2002 · 582 citations · Full text

, , +15

Learning inverse folding from millions of predicted structures

Chloe Hsu, Robert Verkuil, Jason Liu et al. · bioRxiv (Cold Spring Harbor Laboratory) · 2022 · 427 citations · Full text

, , +13

Reconstruction of the Sunspot Group Number: The Backbone Method

Leif Svalgaard, Kenneth H. Schatten · Solar Physics · 2016 · 228 citations · Full text

, , +5

Prediction of protein backbone conformation based on seven structure assignments

Marianne Rooman, Jean-Pierre A. Kocher, Shoshana J. Wodak · Journal of Molecular Biology · 1991 · 192 citations

, , +12

Modelling the polypeptide backbone with ‘spare parts’ from known protein structures

Michel Claessens, Eric Van Cutsem, Ignace Lasters et al. · Protein Engineering Design and Selection · 1989 · 181 citations

, , +14

1–5 of 87

Authors

366

  1. KL
    Kristen L. Mayer

    Indiana University Bloomington, United States

    4 publications · 159 citations

    4

    h-index

  2. AK
    Andrzej Koliński

    University of Warsaw, Poland

    3 publications · 251 citations

    3

    h-index

  3. JH
    James H. Prestegard

    University of Georgia, United States

    3 publications · 129 citations

    3

    h-index

  4. JS
    Jeffrey Skolnick

    Georgia Institute of Technology, United States

    3 publications · 184 citations

    3

    h-index

  5. HV
    Homayoun Valafar

    University of South Carolina, United States

    3 publications · 129 citations

    3

    h-index

1–5 of 366

Institutions

178

  1. Howard Hughes Medical Institute

    Chevy Chase, United States

    4 h-index

    5 publications

    252 citations

  2. Rutgers, The State University of New Jersey

    New Brunswick, United States

    4 h-index

    7 publications

    544 citations

  3. Yale University

    New Haven, United States

    3 h-index

    7 publications

    527 citations

  4. University of California, San Francisco

    San Francisco, United States

    3 h-index

    7 publications

    477 citations

  5. University of California San Diego

    San Diego, United States

    3 h-index

    4 publications

    186 citations

  6. University of Warsaw

    Warsaw, Poland

    3 h-index

    7 publications

    663 citations

  7. University of Georgia

    Athens, United States

    3 h-index

    15 publications

    489 citations

  8. Inserm

    Paris, France

    3 h-index

    15 publications

    604 citations

1–8 of 178

Venues

  1. Journal of Molecular Biology

    JMB · 13 publications · 782 citations

    13

    h-index

  2. Proteins Structure Function and Bioinformatics

    8 publications · 550 citations

    8

    h-index

  3. Journal of Biomolecular NMR

    8 publications · 259 citations

    8

    h-index

  4. Journal of Computational Chemistry

    7 publications · 364 citations

    7

    h-index

  5. Journal of the American Chemical Society

    JACS · 3 publications · 184 citations

    3

    h-index

1–5