Concepedia

Backbone Protection Groups

Backbone Protection Groups is a class of chemical modifiers used in oligonucleotide synthesis that selectively shield the phosphodiester backbone from undesired side reactions during chain assembly, thereby ensuring fidelity and efficiency in the formation of nucleic acid sequences.

38

Publications

1.3K

Citations

144

Authors

50

Institutions

Publications per year

2017–2026

2

Parents

Publications

38

The aspartimide problem in Fmoc‐based SPPS. Part I

M. Mergler, Fritz Dick, B. Sax et al. · Journal of Peptide Science · 2003 · 109 citations · Full text

, , +13

Protein Conformational Stability Probed by Fourier Transform Ion Cyclotron Resonance Mass Spectrometry

Stephen J. Eyles, J. Paul Speir, Gary Kruppa et al. · Journal of the American Chemical Society · 2000 · 77 citations

, , +17

Covalent Capture and Stabilization of Cylindricalβ-Sheet Peptide Assemblies

Thomas D. Clark, Kenji Kobayashi, M. Reza Ghadiri · Chemistry - A European Journal · 1999 · 76 citations · Full text

, , +16

Challenges in the Interpretation of Protein H/D Exchange Data: A Molecular Dynamics Simulation Perspective

Robert G. McAllister, Lars Konermann · Biochemistry · 2015 · 67 citations

, , +17

On-resin solid-phase synthesis of asparagine N-linked glycopeptides: use of N-(2-acetoxy-4-methoxybenzyl)(AcHmb) aspartyl amide-bond protection to prevent unwanted aspartimide formation

John Offer, Martin Quibell, Tony Johnson · Journal of the Chemical Society Perkin Transactions 1 · 1996 · 63 citations

, , +16

1–5 of 38

Authors

144

  1. MQ
    Martin Quibell

    MRC Laboratory of Molecular Biology, United Kingdom

    4 publications · 159 citations

    4

    h-index

  2. MS
    Mitsuo Sekine

    Tokyo Institute of Technology, Japan

    4 publications · 105 citations

    4

    h-index

  3. WP
    Wolfgang Pfleiderer

    University of Konstanz, Germany

    4 publications · 91 citations

    4

    h-index

  4. TJ
    Tony Johnson

    MRC Laboratory of Molecular Biology, United Kingdom

    3 publications · 117 citations

    3

    h-index

  5. TH
    Tsujiaki Hata

    Tokyo Institute of Technology, Japan

    2 publications · 82 citations

    2

    h-index

1–5 of 144

Institutions

50

  1. Tokyo Institute of Technology

    Tokyo, Japan

    4 h-index

    13 publications

    349 citations

  2. University of Konstanz

    Konstanz, Germany

    4 h-index

    9 publications

    214 citations

  3. Tsinghua University

    Beijing, China

    2 h-index

    11 publications

    499 citations

  4. The Wistar Institute

    Philadelphia, United States

    2 h-index

    3 publications

    58 citations

  5. University of Science and Technology of China

    Hefei, China

    2 h-index

    6 publications

    255 citations

  6. The University of Melbourne

    Melbourne, Australia

    2 h-index

    6 publications

    108 citations

  7. Florey Institute of Neuroscience and Mental Health

    Melbourne, Australia

    2 h-index

    6 publications

    108 citations

  8. Universitat de Barcelona

    Barcelona, Spain

    2 h-index

    9 publications

    282 citations

1–8 of 50

Venues

  1. Tetrahedron Letters

    7 publications · 240 citations

    7

    h-index

  2. 4

    h-index

  3. Helvetica Chimica Acta

    4 publications · 91 citations

    4

    h-index

  4. Journal of Peptide Research

    3 publications · 66 citations

    3

    h-index

  5. Nucleic Acids Research

    2 publications · 89 citations

    2

    h-index

1–5