Concepedia

B Cell Receptor Evolution

B Cell Receptor Evolution is a theoretical construct in immunology that characterizes the iterative, selection-driven process by which B cell receptors acquire somatic mutations and undergo affinity-based differentiation to progressively enhance antigen binding specificity and functional efficacy during the humoral immune response.

28

Publications

1.3K

Citations

195

Authors

100

Institutions

Publications per year

2017–2026

12

Parents

Publications

28

Human Marginal Zone B Cells

Jean–Claude Weill, Sandra K. Weller, Claude–Agnès Reynaud · Annual Review of Immunology · 2009 · 389 citations

, , +17

The evolutionary landscape of chronic lymphocytic leukemia treated with ibrutinib targeted therapy

Dan A. Landau, Clare Sun, Daniel Rosebrock et al. · Nature Communications · 2017 · 180 citations · Full text

, , +17

The B7 family of immunoregulatory receptors: A comparative and evolutionary perspective

John D. Hansen, Louis Du Pasquier, Marie‐Paule Lefranc et al. · Molecular Immunology · 2008 · 111 citations

, , +16

Evolution of the B7 family: co-evolution of B7H6 and NKp30, identification of a new B7 family member, B7H7, and of B7's historical relationship with the MHC

Martin F. Flajnik, Tereza Tlapáková, Michael F. Criscitiello et al. · Immunogenetics · 2012 · 85 citations · Full text

, , +16

BAFF‐induced changes in B cell antigen receptor–containing lipid rafts in Sjögren's syndrome

Frédérique d’Arbonneau, Jacques‐Olivier Pers, Valérie Devauchelle et al. · Arthritis & Rheumatism · 2005 · 74 citations · Full text

, , +17

1–5 of 28

Authors

195

  1. GS
    George S. Vassiliou

    Wellcome Sanger Institute, United Kingdom

    3 publications · 90 citations

    3

    h-index

  2. RB
    Rachael Bashford-Rogers

    University of Oxford, United Kingdom

    3 publications · 90 citations

    3

    h-index

  3. PK
    Paul Kellam

    Wellcome Sanger Institute, United Kingdom

    3 publications · 90 citations

    3

    h-index

  4. FA
    F. A. Matsen

    Fred Hutch Cancer Center, United States

    3 publications · 121 citations

    3

    h-index

  5. DN
    D. Noah Sather

    University of Washington, United States

    1 publications · 50 citations

    1

    h-index

1–5 of 195

Institutions

100

  1. Fred Hutch Cancer Center

    Seattle, United States

    4 h-index

    11 publications

    522 citations

  2. University of Cambridge

    Cambridge, United Kingdom

    3 h-index

    7 publications

    168 citations

  3. Wellcome Sanger Institute

    Cambridge, United Kingdom

    3 h-index

    9 publications

    270 citations

  4. Ragon Institute of MGH, MIT and Harvard

    Cambridge, United States

    2 h-index

    2 publications

    48 citations

  5. Centre National de la Recherche Scientifique

    Paris, France

    2 h-index

    4 publications

    332 citations

  6. University of Washington

    Seattle, United States

    2 h-index

    2 publications

    115 citations

  7. Harvard University

    Cambridge, United States

    2 h-index

    8 publications

    210 citations

  8. University College London

    London, United Kingdom

    2 h-index

    5 publications

    217 citations

1–8 of 100

Venues

  1. Frontiers in Immunology

    2 publications · 68 citations

    2

    h-index

  2. Nature Communications

    2 publications · 224 citations

    2

    h-index

  3. Molecular Immunology

    2 publications · 139 citations

    2

    h-index

  4. Molecular Biology and Evolution

    MBE · 2 publications · 78 citations

    2

    h-index

  5. Proceedings of the National Academy of Sciences

    PNAS · 2 publications · 78 citations

    2

    h-index

1–5