• Lipid metabolism and lipoproteins consistently emerge as primary drivers of atherosclerosis, linking serum lipids, lipid fractions, and vascular biology in multiple studies [1], [5], [9], [17], [18], [19].

• Coronary predilection and occlusive pathology are central themes, aligning anatomical vulnerability with thrombosis and myocardial injury across coronary-focused works [4], [10], [14].

• Age, sex, hypertension, and population health framing shape risk and disease trajectory, guiding public health perspectives on coronary atherosclerosis [4], [6], [12], [15].

• Pathology-driven investigations map vascular lesions, arteriosclerosis, and tissue remodeling, establishing morphology as a bridge from biology to clinical outcomes [8], [13], [14], [16].

• Clinical lipidology and lipid-disorder paradigms treat atherosclerosis as a lipid-driven vascular disease, integrating lipoprotein studies with metabolic syndromes to inform risk assessment [1], [2], [3], [11], [19].