Concepedia

Aromatase Pathway

Aromatase Pathway is a biochemical pathway that catalyzes the conversion of androgens into estrogens through the action of the aromatase enzyme, distinguishing it from other steroidogenic pathways by its specific role in estrogen biosynthesis.

902

Publications

44.1K

Citations

4K

Authors

1.2K

Institutions

Publications per year

2017–2026

111

Variants

Aromatase Biosynthetic Pathway

Parents

Publications

902

Alpelisib plus fulvestrant for PIK3CA-mutated, hormone receptor-positive, human epidermal growth factor receptor-2–negative advanced breast cancer: final overall survival results from SOLAR-1

Fabrice André, Eva Ciruelos, Dejan Juric et al. · Annals of Oncology · 2020 · 599 citations · Full text

, , +17

Inhibition of human aromatase by mammalian lignans and isoflavonoid phytoestrogens

Herman Adlercreutz, C. Bannwart, Kristiina Wähälä et al. · The Journal of Steroid Biochemistry and Molecular Biology · 1993 · 546 citations

, , +16

Estrogen biosynthesis proximal to a breast tumor is stimulated by PGE2 via cyclic AMP, leading to activation of promoter II of the CYP19 (aromatase) gene.

Yan Zhao, Veena R. Agarwal, Carole R. Mendelson et al. · Endocrinology · 1996 · 424 citations

, , +16

In Situ Estrogen Production via the Estrone Sulfatase Pathway in Breast Tumors: Relative Importance versus the Aromatase Pathway*

Steven J. Santner, Peter D. Feil, Richard J. Santen · The Journal of Clinical Endocrinology & Metabolism · 1984 · 406 citations

, , +17

Induction and Inhibition of Aromatase (CYP19) Activity by Various Classes of Pesticides in H295R Human Adrenocortical Carcinoma Cells

J. Thomas Sanderson, J.A.K. Boerma, Gideon Lansbergen et al. · Toxicology and Applied Pharmacology · 2002 · 361 citations

, , +14

1–5 of 902

Authors

4K

  1. MD
    Mitch Dowsett

    Royal Marsden Hospital, United Kingdom

    16 publications · 860 citations

    15

    h-index

  2. NH
    Nobuhiro Harada

    Fujita Health University, Japan

    12 publications · 696 citations

    12

    h-index

  3. HS
    Hironobu Sasano

    Tohoku University, Japan

    11 publications · 558 citations

    11

    h-index

  4. RJ
    Richard J. Santen

    Penn State Milton S. Hershey Medical Center, United States

    12 publications · 1K citations

    11

    h-index

  5. AB
    Angela Brodie

    University of Maryland, Baltimore, United States

    11 publications · 687 citations

    11

    h-index

1–5 of 4K

Institutions

1.2K

  1. University of Maryland, Baltimore

    Baltimore, United States

    24 h-index

    92 publications

    5.9K citations

  2. Johns Hopkins University

    Baltimore, United States

    14 h-index

    44 publications

    3.9K citations

  3. Tohoku University

    Sendai, Japan

    13 h-index

    66 publications

    2.3K citations

  4. Fujita Health University

    Toyoake, Japan

    13 h-index

    19 publications

    1K citations

  5. Novartis (Switzerland)

    Basel, Switzerland

    12 h-index

    30 publications

    1.9K citations

  6. The Ohio State University

    Columbus, United States

    12 h-index

    53 publications

    3.1K citations

  7. University of Toronto

    Toronto, Canada

    12 h-index

    25 publications

    2.7K citations

  8. Centre National de la Recherche Scientifique

    Paris, France

    12 h-index

    29 publications

    1.2K citations

1–8 of 1.2K

Venues

  1. 41

    h-index

  2. Breast Cancer Research and Treatment

    54 publications · 2.7K citations

    31

    h-index

  3. Fertility and Sterility

    30 publications · 2.1K citations

    23

    h-index

  4. Molecular and Cellular Endocrinology

    28 publications · 1.2K citations

    21

    h-index

  5. The Journal of Clinical Endocrinology & Metabolism

    JCEM · 24 publications · 1.8K citations

    20

    h-index

1–5