Concepedia

Aptamer Affinity Maturation

Aptamer Affinity Maturation is a methodological process within nucleic acid aptamer evolution that systematically enhances the binding strength and specificity of aptamers to their target molecules through iterative selection and optimization cycles.

16

Publications

705

Citations

94

Authors

46

Institutions

Publications per year

2017–2026

5

Parents

Publications

16

Affinity Improvement of a VEGF Aptamer by <i>in Silico</i> Maturation for a Sensitive VEGF-Detection System

Yoshihiko Nonaka, Wataru Yoshida, Koichi Abe et al. · Analytical Chemistry · 2012 · 111 citations

, , +15

Aptamers as functional nucleic acids:In vitro selection and biotechnological applications

Kyung Man You, Sang Hyun Lee, Sun Bok Lee et al. · Biotechnology and Bioprocess Engineering · 2003 · 95 citations

, , +16

A high-dimensional microfluidic approach for selection of aptamers with programmable binding affinities

Dingran Chang, Zongjie Wang, Connor D. Flynn et al. · Nature Chemistry · 2023 · 92 citations · Full text

, , +13

Selection and characterization of large collections of peptide aptamers through optimized yeast two-hybrid procedures

Marc Bickle, Eric Dusserre, Olivier Moncorgé et al. · Nature Protocols · 2006 · 57 citations

, , +10

In silico maturation of affinity and selectivity of DNA aptamers against aflatoxin B1 for biosensor development

Maryam Mousivand, Laura Anfossi, Kowsar Bagherzadeh et al. · Analytica Chimica Acta · 2020 · 53 citations

, , +14

1–5 of 16

Authors

94

  1. WY
    Wataru Yoshida

    Tokyo University of Agriculture and Technology, Japan

    3 publications · 163 citations

    3

    h-index

  2. KI
    Kazunori Ikebukuro

    Tokyo University of Agriculture and Technology, Japan

    3 publications · 163 citations

    3

    h-index

  3. KA
    Koichi Abe

    Tokyo University of Agriculture and Technology, Japan

    3 publications · 163 citations

    3

    h-index

  4. SF
    Stefano Ferri

    Tokyo University of Agriculture and Technology, Japan

    3 publications · 163 citations

    3

    h-index

  5. KB
    Kowsar Bagherzadeh

    Tehran University of Medical Sciences, Iran

    2 publications · 66 citations

    2

    h-index

1–5 of 94

Institutions

46

  1. Tokyo University of Agriculture and Technology

    Tokyo, Japan

    3 h-index

    21 publications

    975 citations

  2. Agricultural Biotechnology Research Institute of Iran

    Karaj, Iran

    2 h-index

    3 publications

    79 citations

  3. University of Tehran

    Tehran, Iran

    2 h-index

    5 publications

    185 citations

  4. Agricultural Research & Education Organization

    Tehran, Iran

    2 h-index

    3 publications

    79 citations

  5. Rasool Akram Hospital

    Tehran, Iran

    2 h-index

    2 publications

    66 citations

  6. Iran University of Medical Sciences

    Tehran, Iran

    2 h-index

    2 publications

    66 citations

  7. University of Turin

    Turin, Italy

    2 h-index

    3 publications

    119 citations

  8. University of Science and Technology of China

    Hefei, China

    1 h-index

    4 publications

    204 citations

1–8 of 46

Venues

  1. Analytical Chemistry

    2 publications · 145 citations

    2

    h-index

  2. Journal of Bioscience and Bioengineering

    1 publications · 17 citations

    1

    h-index

  3. Nature Protocols

    1 publications · 57 citations

    1

    h-index

  4. Journal of Virological Methods

    1 publications · 50 citations

    1

    h-index

  5. Analytica Chimica Acta

    1 publications · 53 citations

    1

    h-index

1–5