Concepedia

Antibody Format Engineering

Antibody Format Engineering is a recombinant antibody design strategy that systematically modifies the structural architecture of antibody molecules to optimize their functional properties, distinguishing it from other antibody engineering approaches by focusing specifically on the configuration and arrangement of antibody domains, chains, and fusion elements.

22

Publications

770

Citations

149

Authors

55

Institutions

Publications per year

2017–2026

11

Parents

Publications

22

Differential tumor-targeting abilities of three single-domain antibody formats

Andrea M. Bell, Zheng J. Wang, Mehdi Arbabi‐Ghahroudi et al. · Cancer Letters · 2009 · 115 citations · Full text

, , +14

The change of the scFv into the Fab format improves the stability and in vivo toxin neutralization capacity of recombinant antibodies

Verónica Quintero‐Hernández, Víctor Rivelino Juárez-González, Mauricio Ortíz-León et al. · Molecular Immunology · 2006 · 94 citations

, , +15

Enhancement of antibody-dependent cell-mediated cytotoxicity by endowing IgG with FcαRI (CD89) binding

M. Jack Borrok, Nadia Luheshi, Nurten Beyaz et al. · mAbs · 2015 · 67 citations · Full text

, , +17

Alternative antibody formats.

Roland E. Kontermann · PubMed · 2010 · 56 citations

, , +17

Formatted single-domain antibodies can protect mice against infection with influenza virus (H5N2)

M. V. Rutovskaya, Seda A. Saakyan, Irina Y. Gribova et al. · Antiviral Research · 2012 · 54 citations

, , +14

1–5 of 22

Authors

149

  1. RO
    Richard O’Kennedy

    Dublin City University, Ireland

    3 publications · 42 citations

    3

    h-index

  2. HM
    Hui Ma

    Nankai University, China

    2 publications · 26 citations

    2

    h-index

  3. SK
    Sabine Kainz

    Universität Hamburg, Germany

    1 publications · 21 citations

    1

    h-index

  4. FP
    F. Philbert

    Université de Reims Champagne-Ardenne, France

    1 publications · 38 citations

    1

    h-index

  5. XM
    Xiaojie Ma

    University of Florida, United States

    1 publications · 21 citations

    1

    h-index

1–5 of 149

Institutions

55

  1. Dublin City University

    Dublin, Ireland

    3 h-index

    10 publications

    124 citations

  2. University Hospital Heidelberg

    Heidelberg, Germany

    1 h-index

    9 publications

    243 citations

  3. Heidelberg University

    Heidelberg, Germany

    1 h-index

    9 publications

    243 citations

  4. Philochem (Switzerland)

    Otelfingen, Switzerland

    1 h-index

    3 publications

    78 citations

  5. Keio University

    Tokyo, Japan

    1 h-index

    1 publications

    21 citations

  6. German Cancer Research Center

    Heidelberg, Germany

    1 h-index

    1 publications

    27 citations

  7. Utrecht University

    Utrecht, The Netherlands

    1 h-index

    3 publications

    51 citations

  8. Eli Lilly (United States)

    Indianapolis, United States

    1 h-index

    11 publications

    330 citations

1–8 of 55

Venues

  1. Journal of Immunological Methods

    3 publications · 43 citations

    3

    h-index

  2. mAbs

    2 publications · 104 citations

    2

    h-index

  3. Antiviral Research

    1 publications · 54 citations

    1

    h-index

  4. BioDrugs

    1 publications · 21 citations

    1

    h-index

  5. Cancer Letters

    1 publications · 115 citations

    1

    h-index

1–5