Concepedia

Anchored Enzyme Localization

Anchored Enzyme Localization is a methodological framework in cell biology that specifies the spatial targeting of enzymes to cellular membranes through covalent or non-covalent attachment to lipid moieties or membrane-associated proteins, thereby restricting enzymatic activity to specific subcellular domains to regulate signaling pathways and metabolic processes.

9

Publications

817

Citations

32

Authors

15

Institutions

Publications per year

2017–2026

1

Parents

Publications

9

Association of the type II cAMP-dependent protein kinase with a human thyroid RII-anchoring protein. Cloning and characterization of the RII-binding domain.

Daniel W. Carr, Z.E. Hausken, Iain D. C. Fraser et al. · Journal of Biological Chemistry · 1992 · 351 citations · Full text

, , +15

On the surface localization of enzymes in E.coli

Harold C. Neu, L. A. Heppel · Biochemical and Biophysical Research Communications · 1964 · 148 citations

, , +11

Expression of ecto-5′-nucleotidase (eN, CD73) in cell lines from various stages of human melanoma

Rafał Sądej, Józef Spychała, Andrzej C. Składanowski · Melanoma Research · 2006 · 105 citations

, , +11

Isoform-specific Differences between the Type Iα and IIα Cyclic AMP-dependent Protein Kinase Anchoring Domains Revealed by Solution NMR

Poopak Banky, Marceen Glavic Newlon, M. Roy et al. · Journal of Biological Chemistry · 2000 · 56 citations · Full text

, , +17

Regulating Cell Surface Glycosylation by Small Molecule Control of Enzyme Localization

Jennifer J. Kohler, Carolyn R. Bertozzi · Chemistry & Biology · 2003 · 52 citations · Full text

, , +16

1–5 of 9

Authors

32

  1. JS
    J.D. Scott

    Vollum Institute, United States

    1 publications · 351 citations

    1

    h-index

  2. ZH
    Z.E. Hausken

    Vollum Institute, United States

    1 publications · 351 citations

    1

    h-index

  3. RS
    R.E. Stofko-Hahn

    Oregon Health & Science University, United States

    1 publications · 351 citations

    1

    h-index

  4. PT
    Pengfei Tian

    National Institute of Diabetes and Digestive and Kidney Diseases, United States

    1 publications · 18 citations

    1

    h-index

  5. KK
    Kasper K. Sørensen

    University of Copenhagen, Denmark

    1 publications · 18 citations

    1

    h-index

1–5 of 32

Institutions

15

  1. Howard Hughes Medical Institute

    Chevy Chase, United States

    2 h-index

    4 publications

    220 citations

  2. University of California, Berkeley

    Berkeley, United States

    2 h-index

    5 publications

    158 citations

  3. National Institutes of Health

    Bethesda, United States

    1 h-index

    2 publications

    296 citations

  4. Vollum Institute

    Portland, United States

    1 h-index

    4 publications

    1.4K citations

  5. Novozymes (Denmark)

    Copenhagen, Denmark

    1 h-index

    1 publications

    18 citations

  6. Gdańsk Medical University

    Gdansk, Poland

    1 h-index

    2 publications

    210 citations

  7. University of California San Diego

    San Diego, United States

    1 h-index

    6 publications

    336 citations

  8. Oregon Health & Science University

    Portland, United States

    1 h-index

    1 publications

    351 citations

1–8 of 15

Venues

  1. Journal of Biological Chemistry

    JBC · 2 publications · 407 citations

    2

    h-index

  2. Molecular Endocrinology

    1 publications · 45 citations

    1

    h-index

  3. The Journal of Membrane Biology

    1 publications · 14 citations

    1

    h-index

  4. Planta

    1 publications · 28 citations

    1

    h-index

  5. Chemistry & Biology

    1 publications · 52 citations

    1

    h-index

1–5