Concepedia

Amphipol Stabilization

Amphipol Stabilization is a method in membrane protein engineering that utilizes amphipathic polymers to non-covalently stabilize membrane proteins in aqueous solution by shielding their hydrophobic transmembrane domains, thereby maintaining their native conformation and functionality outside lipid bilayer environments.

40

Publications

3.1K

Citations

157

Authors

72

Institutions

Publications per year

2017–2026

3

Parents

Publications

40

Amphipols: Polymers that keep membrane proteins soluble in aqueous solutions

Christophe Tribet, R. Audebert, Jean‐Luc Popot · Proceedings of the National Academy of Sciences · 1996 · 459 citations

, , +17

Maltose–neopentyl glycol (MNG) amphiphiles for solubilization, stabilization and crystallization of membrane proteins

Pil Seok Chae, Søren G. F. Rasmussen, Rohini R. Rana et al. · Nature Methods · 2010 · 452 citations

, , +10

Amphipols From A to Z

J.-L. Popot, Thorsten Althoff, Dominique Bagnard et al. · Annual Review of Biophysics · 2011 · 245 citations · Full text

, , +17

Molecular Architecture and Subunit Organization of TRPA1 Ion Channel Revealed by Electron Microscopy

Teresa L. Cvetkov, Kevin W. Huynh, Matthew R. Cohen et al. · Journal of Biological Chemistry · 2011 · 125 citations · Full text

, , +17

Bacteriorhodopsin/Amphipol Complexes: Structural and Functional Properties

Yann Gohon, Tassadite Dahmane, Rob W.H. Ruigrok et al. · Biophysical Journal · 2008 · 100 citations · Full text

, , +7

1–5 of 40

Authors

157

  1. JP
    Jean‐Luc Popot

    Institut de Biologie Physico-Chimique, France

    18 publications · 1.4K citations

    18

    h-index

  2. FG
    Fabrice Giusti

    Institut de Biologie Physico-Chimique, France

    12 publications · 776 citations

    12

    h-index

  3. CT
    Christophe Tribet

    Centre National de la Recherche Scientifique, France

    10 publications · 1.2K citations

    10

    h-index

  4. BP
    Bernard Pucci

    Université d'Avignon et des Pays de Vaucluse, France

    6 publications · 521 citations

    6

    h-index

  5. PB
    Paola Bazzacco

    Institut de Biologie Physico-Chimique, France

    6 publications · 546 citations

    6

    h-index

1–5 of 157

Institutions

72

  1. Institut de Biologie Physico-Chimique

    Paris, France

    25 h-index

    115 publications

    14.6K citations

  2. Centre National de la Recherche Scientifique

    Paris, France

    19 h-index

    104 publications

    11.5K citations

  3. Sorbonne Université

    Paris, France

    13 h-index

    30 publications

    2.9K citations

  4. Université Paris Cité

    Paris, France

    9 h-index

    29 publications

    1.9K citations

  5. Commissariat à l'Énergie Atomique et aux Énergies Alternatives

    Paris, France

    6 h-index

    25 publications

    1.3K citations

  6. Université d'Avignon et des Pays de Vaucluse

    Avignon, France

    5 h-index

    24 publications

    1.2K citations

  7. University of Copenhagen

    Copenhagen, Denmark

    4 h-index

    11 publications

    1.7K citations

  8. Institut de Biologie Structurale

    Grenoble, France

    4 h-index

    12 publications

    1K citations

1–8 of 72

Venues

  1. Langmuir

    5 publications · 307 citations

    5

    h-index

  2. The Journal of Membrane Biology

    4 publications · 129 citations

    4

    h-index

  3. Biopolymers

    3 publications · 102 citations

    3

    h-index

  4. Biomacromolecules

    3 publications · 125 citations

    3

    h-index

  5. European Biophysics Journal

    2 publications · 119 citations

    2

    h-index

1–5