Concepedia

Alpha Substitution

Alpha Substitution is a chemical reaction in which a hydrogen atom at the alpha position relative to the carboxyl group of a carboxylic acid is replaced by an electrophile, distinguished by the enhanced acidity of the alpha proton due to the electron-withdrawing nature of the adjacent carbonyl group.

52

Publications

1.7K

Citations

158

Authors

42

Institutions

Publications per year

2017–2026

2

Parents

Publications

52

The Alpha Substitution Effect on Phthalocyanine Aggregation

Robert George, Arthur W. Snow, James S. Shirk et al. · Journal of Porphyrins and Phthalocyanines · 1998 · 141 citations

, , +15

The determinants of aggregate energy use in West Germany: factor substitution, technological change, and trade

Heinz Welsch, Carsten Ochsen · Energy Economics · 2004 · 116 citations

, , +16

The α-Effect in the Chemistry of Organic Compounds

A. P. GREKOV · Russian Chemical Reviews · 1978 · 85 citations

, , +15

Substitution at the α-carbons of α,β-unsaturated carbonyl compounds: anti-Michael addition

Elżbieta Lewandowska · Tetrahedron · 2006 · 69 citations

, , +10

Antimicrobial activity against Staphylococcus aureus of semisynthetic injectable streptogramins: RP 59500 and related compounds

J. Barrière, D. H. Bouanchaud, J.M. Paris et al. · Journal of Antimicrobial Chemotherapy · 1992 · 67 citations

, , +13

1–5 of 52

Authors

158

  1. WS
    Walter S. Trahanovsky

    Iowa State University, United States

    2 publications · 44 citations

    2

    h-index

  2. LH
    L. H. Klemm

    University of Oregon, United States

    2 publications · 27 citations

    2

    h-index

  3. ML
    Man‐kit Leung

    National Taiwan University, Taiwan

    2 publications · 44 citations

    2

    h-index

  4. DR
    Daniel R. Muchiri

    University of Oregon, United States

    1 publications · 16 citations

    1

    h-index

  5. MA
    Michael A. Stemniski

    1 publications · 13 citations

    1

    h-index

1–5 of 158

Institutions

42

  1. University of Oregon

    Eugene, United States

    3 h-index

    8 publications

    124 citations

  2. Division of Undergraduate Education

    Arlington, United States

    2 h-index

    3 publications

    43 citations

  3. University of Wisconsin–Madison

    Madison, United States

    2 h-index

    2 publications

    69 citations

  4. University of California, Los Angeles

    Los Angeles, United States

    2 h-index

    8 publications

    118 citations

  5. Payame Noor University

    Tehran, Iran

    1 h-index

    1 publications

    16 citations

  6. Chinese Academy of Sciences

    Beijing, China

    1 h-index

    5 publications

    135 citations

  7. Fulbright Commission

    London, United Kingdom

    1 h-index

    1 publications

    16 citations

  8. University of Washington

    Seattle, United States

    1 h-index

    1 publications

    24 citations

1–8 of 42

Venues

  1. Journal of the American Chemical Society

    JACS · 10 publications · 319 citations

    10

    h-index

  2. The Journal of Organic Chemistry

    JOC · 7 publications · 151 citations

    7

    h-index

  3. Journal of Heterocyclic Chemistry

    2 publications · 27 citations

    2

    h-index

  4. Energy Economics

    2 publications · 146 citations

    2

    h-index

  5. Chemical Physics Letters

    1 publications · 11 citations

    1

    h-index

1–5