Concepedia

Ala Synthase Regulation

"ALA Synth OECD Regulation" is a biochemical regulatory mechanism that controls the activity and expression of 5-aminolevulinate synthase, the rate-limiting enzyme in heme biosynthesis, thereby modulating heme production in response to cellular demands and metabolic signals.

105

Publications

4.8K

Citations

362

Authors

115

Institutions

Publications per year

2017–2026

8

Parents

Publications

105

Chronic activation of AMP kinase results in NRF-1 activation and mitochondrial biogenesis

Raynald Bergeron, Jian Ren, Kevin S. Cadman et al. · American Journal of Physiology-Endocrinology and Metabolism · 2001 · 560 citations

, , +17

Induction of aminolevulinate synthase and porphyrins in cultured liver cells maintained in chemically defined medium. Permissive effects of hormones on induction process.

Shigeru Sassa, Attallah Kappas · Journal of Biological Chemistry · 1977 · 160 citations · Full text

, , +14

Aerobic and anaerobic regulation in Rhodobacter sphaeroides 2.4.1: the role of the fnrL gene

Jill H. Zeilstra-Ryalls, Samuel Kaplan · Journal of Bacteriology · 1995 · 133 citations · Full text

, , +15

Lon Peptidase 1 (LONP1)-dependent Breakdown of Mitochondrial 5-Aminolevulinic Acid Synthase Protein by Heme in Human Liver Cells

Qing Tian, Ting Li, Weihong Hou et al. · Journal of Biological Chemistry · 2011 · 132 citations · Full text

, , +17

Heme regulates hepatic 5-aminolevulinate synthase mRNA expression by decreasing mRNA half-life and not by altering its rate of transcription

Joshua W. Hamilton, William J. Bement, Peter R. Sinclair et al. · Archives of Biochemistry and Biophysics · 1991 · 116 citations

, , +17

1–5 of 105

Authors

362

  1. SS
    Shigeru Sassa

    Rockefeller University, United States

    7 publications · 350 citations

    7

    h-index

  2. MY
    Masayuki Yamamoto

    Tohoku University, Japan

    7 publications · 230 citations

    7

    h-index

  3. BK
    Brian K. May

    The University of Adelaide, Australia

    6 publications · 386 citations

    6

    h-index

  4. NH
    Norio Hayashi

    The University of Osaka, Japan

    6 publications · 235 citations

    6

    h-index

  5. MM
    Michael Moore

    Stobhill Hospital, United Kingdom

    4 publications · 133 citations

    4

    h-index

1–5 of 362

Institutions

115

  1. Tohoku University

    Sendai, Japan

    8 h-index

    18 publications

    419 citations

  2. The University of Adelaide

    Adelaide, Australia

    7 h-index

    22 publications

    1.4K citations

  3. Western Infirmary

    Glasgow, United Kingdom

    5 h-index

    21 publications

    754 citations

  4. University of South Florida

    Tampa, United States

    4 h-index

    14 publications

    385 citations

  5. Michigan State University

    East Lansing, United States

    4 h-index

    7 publications

    432 citations

  6. University of Tsukuba

    Tsukuba, Japan

    4 h-index

    7 publications

    191 citations

  7. Rockefeller University Hospital

    New York, United States

    3 h-index

    11 publications

    585 citations

  8. University of Wales

    Cardiff, United Kingdom

    3 h-index

    13 publications

    439 citations

1–8 of 115

Venues

  1. Journal of Biological Chemistry

    JBC · 14 publications · 940 citations

    14

    h-index

  2. Journal of Bacteriology

    JB · 8 publications · 556 citations

    8

    h-index

  3. Biochemical Journal

    BJ · 7 publications · 234 citations

    7

    h-index

  4. PLANT PHYSIOLOGY

    4 publications · 172 citations

    4

    h-index

  5. PubMed

    Repository · 4 publications · 113 citations

    4

    h-index

1–5