Concepedia

Aggregate Clearance

Aggregate Clearance is a biological process that refers to the cellular mechanism responsible for the recognition, degradation, and removal of misfolded or aggregated proteins to maintain proteostasis.

38

Publications

3.1K

Citations

272

Authors

107

Institutions

Publications per year

2017–2026

17

Parents

Publications

38

Clearance of α-Synuclein Oligomeric Intermediates via the Lysosomal Degradation Pathway

He-Jin Lee, Farnaz Khoshaghideh, Smita S. Patel et al. · Journal of Neuroscience · 2004 · 450 citations · Full text

, , +17

UBQLN2 Mediates Autophagy-Independent Protein Aggregate Clearance by the Proteasome

Roland Hjerpe, John S. Bett, Matthew J. Keuss et al. · Cell · 2016 · 310 citations · Full text

, , +13

Intracellular Protein Aggregation Is a Proximal Trigger of Cardiomyocyte Autophagy

Paul Tannous, Andriy Nemchenko, Jeff M. Berry et al. · Circulation · 2008 · 243 citations · Full text

, , +17

Identification of an Autophagy Defect in Smokers’ Alveolar Macrophages

Martha M. Monick, Linda S. Powers, Katherine S. Walters et al. · The Journal of Immunology · 2010 · 233 citations · Full text

, , +17

p62, Ref(2)P and ubiquitinated proteins are conserved markers of neuronal aging, aggregate formation and progressive autophagic defects

Bryan J. Bartlett, Pauline Isakson, Jan Lewerenz et al. · Autophagy · 2011 · 219 citations

, , +15

1–5 of 38

Authors

272

  1. AS
    Anne Simonsen

    University of Oslo, Norway

    3 publications · 291 citations

    3

    h-index

  2. AY
    Ai Yamamoto

    Columbia University, United States

    3 publications · 233 citations

    3

    h-index

  3. SG
    Saurabh Gautam

    Indian Institute of Technology Delhi, India

    3 publications · 180 citations

    3

    h-index

  4. FU
    F. Ulrich Hartl

    Max Planck Institute of Biochemistry, Germany

    3 publications · 180 citations

    3

    h-index

  5. MM
    Matthias M. Schneider

    University of Cambridge, United Kingdom

    2 publications · 96 citations

    2

    h-index

1–5 of 272

Institutions

107

  1. University of Göttingen

    Göttingen, Germany

    3 h-index

    7 publications

    513 citations

  2. University Medical Center Groningen

    Groningen, The Netherlands

    3 h-index

    5 publications

    228 citations

  3. Columbia University

    New York, United States

    3 h-index

    6 publications

    484 citations

  4. Max Planck Institute of Biochemistry

    Martinsried, Germany

    3 h-index

    20 publications

    1.5K citations

  5. University of Oslo

    Oslo, Norway

    3 h-index

    5 publications

    559 citations

  6. The University of Texas Southwestern Medical Center

    Dallas, United States

    3 h-index

    19 publications

    2.5K citations

  7. University of Groningen

    Groningen, The Netherlands

    3 h-index

    5 publications

    228 citations

  8. University of Cambridge

    Cambridge, United Kingdom

    2 h-index

    20 publications

    960 citations

1–8 of 107

Venues

  1. Autophagy

    5 publications · 379 citations

    5

    h-index

  2. Nature Communications

    4 publications · 255 citations

    4

    h-index

  3. Journal of Cell Science

    2 publications · 54 citations

    2

    h-index

  4. Journal of Neurochemistry

    JNC · 2 publications · 102 citations

    2

    h-index

  5. Journal of Neuroscience

    2 publications · 619 citations

    2

    h-index

1–5