Concepedia

Activity-dependent Synaptic Elimination

Activity-Dependent Synaptic Elimination is a neurobiological process within synaptic refinement whereby less active synaptic connections are selectively weakened and removed during neural development based on the functional activity levels of pre- and postsynaptic neurons.

60

Publications

6.9K

Citations

268

Authors

81

Institutions

Publications per year

2017–2026

10

Parents

Publications

60

Schizophrenia: Caused by a fault in programmed synaptic elimination during adolescence?

Irwin Feinberg · Journal of Psychiatric Research · 1982 · 1.4K citations

, , +12

Selective elimination of glutamatergic synapses on striatopallidal neurons in Parkinson disease models

Michelle Day, Zhongfeng Wang, Jun Ding et al. · Nature Neuroscience · 2006 · 747 citations

, , +17

Activity-Dependent Validation of Excitatory versus Inhibitory Synapses by Neuroligin-1 versus Neuroligin-2

Alexander A. Chubykin, Deniz Atasoy, Mark R. Etherton et al. · Neuron · 2007 · 588 citations · Full text

, , +16

Principles of Long-Term Dynamics of Dendritic Spines

Nobuaki Yasumatsu, M Matsuzaki, Takashi Miyazaki et al. · Journal of Neuroscience · 2008 · 336 citations · Full text

, , +17

Expression of Neural Proteoglycans Correlates with the Acquisition of Mature Neuronal Properties in the Mammalian Brain

Susan Hockfield, Robert G. Kalb, S Zaremba et al. · Cold Spring Harbor Symposia on Quantitative Biology · 1990 · 268 citations

, , +17

1–5 of 60

Authors

268

  1. DC
    David C. Van Essen

    Washington University in St. Louis, United States

    5 publications · 215 citations

    5

    h-index

  2. MK
    Masanobu Kano

    The University of Tokyo, Japan

    4 publications · 540 citations

    4

    h-index

  3. PG
    Phillip G. Nelson

    National Institutes of Health, United States

    4 publications · 198 citations

    4

    h-index

  4. MB
    Mario Buffelli

    University of Verona, Italy

    3 publications · 94 citations

    3

    h-index

  5. MW
    Masahiko Watanabe

    Hokkaido University, Japan

    3 publications · 413 citations

    3

    h-index

1–5 of 268

Institutions

81

  1. The University of Tokyo

    Tokyo, Japan

    6 h-index

    21 publications

    3.4K citations

  2. Stanford University

    Stanford, United States

    5 h-index

    34 publications

    5.4K citations

  3. National Institutes of Health

    Bethesda, United States

    5 h-index

    17 publications

    673 citations

  4. California Institute of Technology

    Pasadena, United States

    5 h-index

    12 publications

    548 citations

  5. Japan Science and Technology Agency

    Tokyo, Japan

    4 h-index

    6 publications

    968 citations

  6. Eunice Kennedy Shriver National Institute of Child Health and Human Development

    Bethesda, United States

    4 h-index

    9 publications

    465 citations

  7. Howard Hughes Medical Institute

    Chevy Chase, United States

    4 h-index

    12 publications

    2.1K citations

  8. University of California, San Francisco

    San Francisco, United States

    4 h-index

    26 publications

    5.6K citations

1–8 of 81

Venues

  1. Journal of Neuroscience

    7 publications · 820 citations

    7

    h-index

  2. Neuron

    6 publications · 1.1K citations

    6

    h-index

  3. Nature

    4 publications · 576 citations

    4

    h-index

  4. Developmental Biology

    4 publications · 155 citations

    4

    h-index

  5. Journal of Neuroscience Research

    JNR · 3 publications · 101 citations

    3

    h-index

1–5