Concepedia

Activity-dependent Synapse Refinement

Activity-Dependent Synapse Refinement is a biological mechanism within neural development whereby synaptic connections are selectively stabilized or eliminated based on neuronal activity patterns, serving to optimize circuit functionality and maintain excitatory-inhibitory balance.

43

Publications

4.5K

Citations

212

Authors

79

Institutions

Publications per year

2017–2026

7

Parents

Publications

43

Local GABA Circuit Control of Experience-Dependent Plasticity in Developing Visual Cortex

Takao K. Hensch, Michela Fagiolini, Nobuko Mataga et al. · Science · 1998 · 923 citations · Full text

, , +17

The NO hypothesis: possible effects of a short-lived, rapidly diffusible signal in the development and function of the nervous system.

Joseph A. Gally, P. Read Montague, George N. Reeke et al. · Proceedings of the National Academy of Sciences · 1990 · 648 citations

, , +17

MEF2C, a transcription factor that facilitates learning and memory by negative regulation of synapse numbers and function

Ana C. Barbosa, Mi-Sung Kim, Mert Ertunç et al. · Proceedings of the National Academy of Sciences · 2008 · 310 citations · Full text

, , +17

Neurotrophin release by neurotrophins: Implications for activity-dependent neuronal plasticity

Marco Canossa, Oliver Griesbeck, Benedikt Berninger et al. · Proceedings of the National Academy of Sciences · 1997 · 264 citations

, , +17

Activity-Dependent Synaptogenesis: Regulation by a CaM-Kinase Kinase/CaM-Kinase I/βPIX Signaling Complex

Takeo Saneyoshi, Gary A. Wayman, Dale A. Fortin et al. · Neuron · 2008 · 223 citations · Full text

, , +14

1–5 of 43

Authors

212

  1. CR
    Charles R. Tessier

    Indiana University School of Medicine

    2 publications · 212 citations

    2

    h-index

  2. MW
    Masahiko Watanabe

    Hokkaido University, Japan

    2 publications · 173 citations

    2

    h-index

  3. NT
    Nien‐Pei Tsai

    University of Minnesota Medical Center, United States

    2 publications · 95 citations

    2

    h-index

  4. KB
    Kendal Broadie

    Vanderbilt University, United States

    2 publications · 215 citations

    2

    h-index

  5. MM
    Masayoshi Mishina

    The University of Tokyo, Japan

    2 publications · 84 citations

    2

    h-index

1–5 of 212

Institutions

79

  1. Vanderbilt University

    Nashville, United States

    4 h-index

    10 publications

    715 citations

  2. The University of Tokyo

    Tokyo, Japan

    3 h-index

    8 publications

    551 citations

  3. John F. Kennedy Center for the Performing Arts

    Washington D.C., United States

    2 h-index

    4 publications

    430 citations

  4. The University of Texas Southwestern Medical Center

    Dallas, United States

    2 h-index

    13 publications

    2.4K citations

  5. University of California, Davis

    Davis, United States

    2 h-index

    24 publications

    3.9K citations

  6. Harvard University

    Cambridge, United States

    2 h-index

    8 publications

    372 citations

  7. Yale University

    New Haven, United States

    2 h-index

    5 publications

    251 citations

  8. Johns Hopkins Medicine

    Baltimore, United States

    2 h-index

    24 publications

    3.5K citations

1–8 of 79

Venues

  1. Journal of Neuroscience

    8 publications · 591 citations

    8

    h-index

  2. Proceedings of the National Academy of Sciences

    PNAS · 5 publications · 1.4K citations

    5

    h-index

  3. Neuron

    3 publications · 358 citations

    3

    h-index

  4. Journal of Neurophysiology

    JN · 3 publications · 85 citations

    3

    h-index

  5. Journal of Neurobiology

    2 publications · 60 citations

    2

    h-index

1–5