Concepedia

Activity-dependent Synapse Elimination

Activity-Dependent Synapse Elimination is a biological process within synaptic remodeling whereby specific synapses are selectively pruned or removed in response to neural activity patterns, distinguishing it from activity-independent mechanisms by its reliance on functional activity to drive structural changes in neuronal circuits.

68

Publications

4.9K

Citations

273

Authors

91

Institutions

Publications per year

2017–2026

16

Parents

Publications

68

Activity-Dependent Validation of Excitatory versus Inhibitory Synapses by Neuroligin-1 versus Neuroligin-2

Alexander A. Chubykin, Deniz Atasoy, Mark R. Etherton et al. · Neuron · 2007 · 588 citations · Full text

, , +16

Synapse elimination and learning rules co-regulated by MHC class I H2-Db

Hanmi Lee, Barbara K. Brott, Lowry A. Kirkby et al. · Nature · 2014 · 233 citations

, , +15

Synapse elimination accompanies functional plasticity in hippocampal neurons

Natalia Bastrikova, Gregory A. Gardner, Jeff Reece et al. · Proceedings of the National Academy of Sciences · 2008 · 191 citations · Full text

, , +17

Role of pro-brain-derived neurotrophic factor (proBDNF) to mature BDNF conversion in activity-dependent competition at developing neuromuscular synapses

H. Shawn Je, Feng Yang, Yuanyuan Ji et al. · Proceedings of the National Academy of Sciences · 2012 · 189 citations · Full text

, , +17

Critical Period for Activity-Dependent Synapse Elimination in Developing Cerebellum

Sho Kakizawa, Miwako Yamasaki, Masahiko Watanabe et al. · Journal of Neuroscience · 2000 · 176 citations · Full text

, , +17

1–5 of 68

Authors

273

  1. MA
    María A. Lanuza

    Universitat Rovira i Virgili, Spain

    5 publications · 185 citations

    5

    h-index

  2. AC
    Alberto Cangiano

    University of Verona, Italy

    5 publications · 218 citations

    5

    h-index

  3. MB
    Mario Buffelli

    University of Verona, Italy

    5 publications · 246 citations

    5

    h-index

  4. NG
    Neus García

    Universitat Rovira i Virgili, Spain

    4 publications · 147 citations

    4

    h-index

  5. JT
    Josep Tomàs

    Universitat Rovira i Virgili, Spain

    4 publications · 147 citations

    4

    h-index

1–5 of 273

Institutions

91

  1. National Institutes of Health

    Bethesda, United States

    7 h-index

    21 publications

    1.7K citations

  2. The University of Tokyo

    Tokyo, Japan

    6 h-index

    20 publications

    1.8K citations

  3. University of Verona

    Verona, Italy

    5 h-index

    21 publications

    869 citations

  4. Universitat Rovira i Virgili

    Tarragona, Spain

    5 h-index

    33 publications

    1.1K citations

  5. Stanford University

    Stanford, United States

    5 h-index

    34 publications

    5.4K citations

  6. The University of Texas at Austin

    Austin, United States

    4 h-index

    5 publications

    506 citations

  7. Japan Science and Technology Agency

    Tokyo, Japan

    4 h-index

    6 publications

    648 citations

  8. Eunice Kennedy Shriver National Institute of Child Health and Human Development

    Bethesda, United States

    4 h-index

    9 publications

    465 citations

1–8 of 91

Venues

  1. Journal of Neuroscience

    11 publications · 709 citations

    11

    h-index

  2. Proceedings of the National Academy of Sciences

    PNAS · 8 publications · 814 citations

    8

    h-index

  3. Neuron

    6 publications · 1.2K citations

    6

    h-index

  4. Nature

    3 publications · 499 citations

    3

    h-index

  5. Developmental Biology

    3 publications · 144 citations

    3

    h-index

1–5