Concepedia

Activity-based Imaging

Activity-Based Imaging is a molecular imaging technique that selectively visualizes enzymatically active proteins in their functional state by exploiting substrate-derived probes possessing both a recognition motif specific to the target enzyme’s catalytic site and a reporter group enabling detection.

83

Publications

7K

Citations

530

Authors

197

Institutions

Publications per year

2017–2026

35

Parents

Publications

83

Genetically encoded calcium indicators for multi-color neural activity imaging and combination with optogenetics

Jasper Akerboom, Nicole Carreras Calderón, Lin Tian et al. · Frontiers in Molecular Neuroscience · 2013 · 752 citations · Full text

, , +16

Noninvasive optical imaging of cysteine protease activity using fluorescently quenched activity-based probes

Galia Blum, Georges von Degenfeld, Milton Merchant et al. · Nature Chemical Biology · 2007 · 464 citations

, , +16

Dynamic imaging of protease activity with fluorescently quenched activity-based probes

Galia Blum, Stefanie Mullins, Kinneret Keren et al. · Nature Chemical Biology · 2005 · 359 citations

, , +16

A “Smart” Magnetic Resonance Imaging Agent That Reports on Specific Enzymatic Activity

Rex Moats, Scott E. Fraser, Thomas J. Meade · Angewandte Chemie International Edition in English · 1997 · 331 citations

, , +14

Direct visualization of serine hydrolase activities in complex proteomes using fluorescent active site-directed probes

Matthew P. Patricelli, Dan K. Giang, Lisa M. Stamp et al. · PROTEOMICS · 2001 · 280 citations

, , +15

1–5 of 83

Authors

530

  1. MB
    Matthew Bogyo

    Stanford University, United States

    11 publications · 1.4K citations

    11

    h-index

  2. GB
    Galia Blum

    Hebrew University of Jerusalem, Israel

    5 publications · 1.1K citations

    5

    h-index

  3. LE
    Laura E. Edgington‐Mitchell

    The University of Melbourne, Australia

    5 publications · 354 citations

    5

    h-index

  4. MD
    Marcin Drąg

    Wrocław University of Science and Technology, Poland

    5 publications · 512 citations

    5

    h-index

  5. MV
    Martijn Verdoes

    Radboud University Nijmegen, Netherlands

    5 publications · 390 citations

    5

    h-index

1–5 of 530

Institutions

197

  1. Stanford University

    Stanford, United States

    11 h-index

    48 publications

    6.4K citations

  2. Harvard University

    Cambridge, United States

    5 h-index

    29 publications

    3.4K citations

  3. Wrocław University of Science and Technology

    Wroclaw, Poland

    5 h-index

    15 publications

    1.6K citations

  4. Sanford Burnham Prebys Medical Discovery Institute

    La Jolla, United States

    4 h-index

    17 publications

    1.8K citations

  5. Jožef Stefan Institute

    Ljubljana, Slovenia

    4 h-index

    10 publications

    1.1K citations

  6. University of Arizona

    Tucson, United States

    4 h-index

    18 publications

    659 citations

  7. Discovery Institute

    Seattle, United States

    3 h-index

    14 publications

    1.3K citations

  8. University of California, Berkeley

    Berkeley, United States

    3 h-index

    14 publications

    628 citations

1–8 of 197

Venues

  1. Journal of the American Chemical Society

    JACS · 13 publications · 1.2K citations

    13

    h-index

  2. Angewandte Chemie International Edition

    8 publications · 497 citations

    8

    h-index

  3. Angewandte Chemie

    5 publications · 137 citations

    5

    h-index

  4. Proceedings of the National Academy of Sciences

    PNAS · 3 publications · 328 citations

    3

    h-index

  5. Chemical Science

    3 publications · 240 citations

    3

    h-index

1–5